Nicholas Frank | PhD, DVM, BSc. Hons., DACVIM

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• Professor
• Associate Dean for Academic Affairs
• Large Animal Internal Medicine
• Internal Medicine, Endocrinology, Obesity, and Laminitis

Education

• PhD, Purdue University, 2002
• DVM, Purdue University, 1993
• BSc. Hons., Biology University of North Carolina, 1989

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Board Certifications

• American College of Veterinary Internal Medicine (ACVIM)

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Research Activities

• Internal medicine
• Comparative endocrinology
• Metabolism
• Nutrition
• Gastroenterology

Selected Research Projects

• Endotoxemia as a predisposing factor for laminitis
• Effects of clinical endotoxemia on glucose metabolism in horses
• Levothyroxine as a treatment for insulin resistance
• Effects of resting insulin sensitivity on the acute response to endotoxin in horses
• Effects of combining endotoxemia and alimentary carbohydrate overload on glucose and insulin dynamics in horses
• Improved diagnosis and monitoring of equine endocrine disorders
• Development of an optimal protocol for evaluating insulin secretion and sensitivity in horses
• A study of the alterations in glucose and lipid metabolism that accompany the development of laminitis in horses
• Evaluating the effects of endotoxin on glucose dynamics in horses using intravenous glucose tolerance test and euglycemic hyperinsulinemic clamp techniques

Research and Clinical Interests

• Diagnosis and management of endocrine disorders
• Equine Metabolic Syndrome
• Cushings disease
• Laminitis
• Endotoxemia
• Obesity
• Insulin resistance
• Diabetes mellitus
• Incretin hormones
• Adipokines
• Electrolyte disorders
• Nutritional diseases
• Gastroenterology
• Geriatric medicine
• Neonatology

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Additional Information

Professional organizations

• American Veterinary Medical Association
• American College of Veterinary Internal Medicine

Research Sponsor Interest

• American College of Veterinary Internal Medicine Foundation
• American Quarter Horse Foundation
• Grayson Jockey Club Foundation
• United States Equestrian Federation