Cummings School of Veterinary Medicine at Tufts University
Sangun Lee

Research Assistant Professor

Campus Phone:
508-887-4564
x84564

Education

  • PhD –University of Idaho, 2003
  • MS – Seoul National University, South Korea, 1995
  • DVM – Seoul National University, South Korea, 1991
  1. J. Hellen Amuguni, Sangun Lee, Kathryn O. Kerstein, David W. Brown, Boris R. Belitsky, John E. Herrmann, Gerald T. Keusch, Abraham L. Sonenshein, and Saul Tzipori (2012) Sublingual immunization with engineered Bacillus subtilis strain expressing tetanus toxin fragment C induces systemic and mucosal immune responses in piglets. Microbes and Infection 14:447-56.
  2. Sangun Lee, Yanhai Wang, Sung Ouk Kim, and Jiahuai Han (2011) AMPD3 is involved in anthrax lethal toxin-induced macrophage cell death. Protein & Cell 2:564-72.
  3. J. Hellen Amuguni*, Sangun Lee*, John E. Herrmann, Abraham L. Sonenshein, and Saul Tzipori (2011) Sublingually administered Bacillus subtilis cells expressing tetanus toxin C fragment induce protective systemic and mucosal antibodies against tetanus toxin in mice. Vaccine 29:4778-84.  *contributed equally
  4. Sangun Lee, Boris R. Belitsky, David W. Brown, James P. Brinker, Kathy O. Kerstein, John E. Herrmann, Gerald T. Keusch, Abraham L. Sonenshein , and Saul Tzipori (2010) Efficacy, heat stability and safety of intranasally administered Bacillus subtilis spore or vegetative cell vaccines expressing tetanus toxin fragment C. Vaccine
  5. Sangun Lee, Boris R. Belitsky, James P. Brinker, Kathy O. Kerstein, David W. Brown, Gerald T. Keusch, Saul Tzipori, Abraham L. Sonenshein , John D. Clements , and John E. Herrmann (2010) Development of a Bacillus subtilis-based rotavirus vaccine. Clinical and Vaccine Immunology 17:1647-55.

General Research Interests

  • Vaccine development
  • Host-microbe interaction
  • Microbial pathogenesis

Selected Research Projects

  • Immunization strategy for non-living Shigella vaccines
  • Development of Bacillus subtilis vaccine platforms for heat-stable, needle-free vaccines
  • Effective delivery of the therapeutic antibodies using Bacillus subtilis