Cummings School of Veterinary Medicine at Tufts University
Sandra Ayres

Assistant Professor

Goat Reproduction, Transgenics, Cloning, Theriogenology
Section of Neuroscience and Reproductive Biology

Campus Phone:
508-839-7956
x84605

Fax:
508-839-7091

Education

  • DVM with Thesis - Tufts University - 1993
  • MA - Duke University - 1973
  • BS - Duke University - 1971

Board Certification

  • American College of Theriogenologists, 1999
  1. Ebert, K. M., DiTullio, P., Barry, C.A., Schindler, J.E., Ayres, S.L., Smith, T.E., Pellerin, L.J., Meade, H.M., Denman, J., Roberts, B., Induction of human tissue plasminogen activator in the mammary gland of transgenic goats. Bio/Tech., 12:699-702, 1994.
  2. Ayres, S.L., Wagner, P., Perirectal abscess in an American Miniature horse. Equine Practice, 16(9):33-35, 1994.
  3. Baguisi A., Behboobi E., Melican D.T., Pollock J.S., Destrempes M.M., Williams, J.L., Nims, S.D., Porter C.A., Midura P., Palacios M.J., Ayres, S.L., Denniston R.S., Hayes M.L., Ziomek C.A., Meade H.M., Godke R.A., Gavin W.G., Overtröm E.W., Echelard Y., Production of goats by somatic cell nuclear transfer. Nature Biotech., 15(5):456-461, 1999.
  4. Karuri, A.R., Ayres, S., Kumar, M.S.A., Regional distribution of gonadotropin-releasing hormone, beta-endorphin and met-enkephalin-like immunoreactivities in the central nervous system of the goat. Brain Res. Bull., 51:63-68, 2000
  5. Singer, L.A., Kumar, M.S.A., Gavin, W., Ayres, S.L., Predicting the onset of parturition in the goat by determining progesterone levels by enzyme immunoassay. Small Rum. Res. 52:203-209, 2004.
  6. Behboodi E., Ayres S.L., Memili E., O'coin M., Chen L.H., Reggio B.C., Landry A.M., Gavin W.G., Meade H.M., Godke R.A., Echelard Y. Health and reproductive profiles of malaria antigen-producing transgenic goats derived by somatic cell nuclear transfer. Cloning Stem Cells 7:107-118, 2005.
  7. Honaramooz, A., Behboodi, E., Hausler, C.L., Blash, S., Ayres, S., Azuma, C., Echelard, Y., Dobrinski, I. Depletion of endogenous germ cells in male pigs and goats in preparation for germ cell transplantation. J. Androl. 26: 698-705, 2005.
  8. Honaramooz, A., Megee, S., Zeng, W., Destrempes, M.M., Overton, S.A., Luo, J., Galantino-Homer, H., Modelski, M., Chen, F., Blash, S., Melican, D.T., Gavin, W.G., Ayres S., Yang, F., Wang , P.J., Echelard, Y., Dobrinski, I. Adeno-associated virus (AAV) -mediated transduction of male germ line stem cells results in transgene transmission after germ cell transplantation. FASEB J. 22(2):374-82, 2008.
  9. Dorosko SM, Ayres SL, Connor RI. Induction of HIV-1 MPR(649-684)-specific IgA and IgG antibodies in caprine colostrum using a peptide-based vaccine. Vaccine 26(42):5416-5422, 2008.
  10. Ayres, SL. Early apoptosis in follicular versus ovulated oocytes in superovulated goats. Clin Theriogenology 2(3):387, 2010.

General Research Interests

  • Caprine Reproduction: Advanced reproductive techniques, particularly in relationship to transgenics and cloning.

Selected Research Projects

  • Production of Cloned Goats
  • Superovulation in Goats without the Use of Exogenous Progesterone
  • Use of a Vital Fluorescent Stain to Detect Apoptosis in Oocytes and Embryos
  • Development of a Short Progesterone Protocol for Superovulation in Goats

Research Interests by Area

Reproductive Biology and Neuroscience
  • Refinement of oocyte collection in the goat

Major Specialized Equipment

  • Fluorescence microscope
  • Microinjection microscope