Roderick T. Bronson - DVM, BA

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Professor
Pathology, Markers of Aging
Pathology

Campus Phone:
617-432-2409

Education

  • DVM - University of California, Davis - 1972
  • BA - University of California, Berkeley - 1964

Board Certification

  • American College of Veterinary Pathology
  1. Hwang, I., Oh, H., Santo, E., Kim, D.-Y., Chen, J.W., Bronson, R.T., Locasale, J.W., Na, Y., Lee, J., Reed, S., Toth, M., Yu, W.H., Muller, F.L., Paik, J. 2018. FOXO protects against age-progressive axonal degeneration. Aging Cell.
  2. Chen, M., Zhang, J., Sampieri, K., Clohessy, J.G., Mendez, L., Gonzalez-Billalabeitia, E., Liu, X.-S., Lee, Y.-R., Fung, J., Katon, J.M., Menon, A.V., Webster, K.A., Ng, C., Palumbieri, M.D., Diolombi, M.S., Breitkopf, S.B., Teruya-Feldstein, J., Signoretti, S., Bronson, R.T., Asara, J.M., Castillo-Martin, M., Cordon-Cardo, C., Pandolfi, P.P. 2018. An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer. Nature Genetics.
  3. Geng, Y., Michowski, W., Chick, J.M., Wang, Y.E., Emmanuelle Jecrois, M., Sweeney, K.E., Liu, L., Han, R.C., Ke, N., Zagozdzon, A., Sicinska, E., Bronson, R.T., Gygi, S.P., Sicinski, P. 2018. Kinase-independent function of E-type cyclins in liver cancer. Proceedings of the National Academy of Sciences of the United States of America.
  4. Lee, S.-G., Mikhalchenko, A.E., Yim, S.H., Lobanov, A.V., Park, J.-K., Choi, K.-H., Bronson, R.T., Lee, C.-K., Park, T.J., Gladyshev, V.N. 2017. Naked Mole Rat Induced Pluripotent Stem Cells and Their Contribution to Interspecific Chimera. Stem Cell Reports.
  5. Romero, R., Sayin, V.I., Davidson, S.M., Bauer, M.R., Singh, S.X., Leboeuf, S.E., Karakousi, T.R., Ellis, D.C., Bhutkar, A., Sánchez-Rivera, F.J., Subbaraj, L., Martinez, B., Bronson, R.T., Prigge, J.R., Schmidt, E.E., Thomas, C.J., Goparaju, C., Davies, A., Dolgalev, I., Heguy, A., Allaj, V., Poirier, J.T., Moreira, A.L., Rudin, C.M., Pass, H.I., Vander Heiden, M.G., Jacks, T., Papagiannakopoulos, T. 2017. Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis. Nature Medicine.
  6. Otto, T., Candido, S.V., Pilarz, M.S., Sicinska, E., Bronson, R.T., Bowden, M., Lachowicz, I.A., Mulry, K., Fassl, A., Han, R.C., Jecrois, E.S., Sicinski, P. 2017. Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proceedings of the National Academy of Sciences of the United States of America.
  7. Wang, Z., Zheng, Q., Zhang, H., Bronson, R.T., Madsen, J.C., Sachs, D.H., Huang, C.A., Wang, Z. 2017. Ontak-like human IL-2 fusion toxin. Journal of Immunological Methods.
  8. Morse, K., Kimizuka, Y., Chan, M.P.K., Shibata, M., Shimaoka, Y., Takeuchi, S., Forbes, B., Nirschl, C., Li, B., Zeng, Y., Bronson, R.T., Katagiri, W., Shigeta, A., Srbulescu, R.F., Chen, H., Tan, R.Y.Y., Tsukada, K., Brauns, T., Gelfand, J., Sluder, A., Locascio, J.J., Poznansky, M.C., Anandasabapathy, N., Kashiwagi, S. 2017. Near-infrared 1064 nm laser modulates migratory dendritic cells to augment the immune response to intradermal influenza vaccine. Journal of Immunology.
  9. Riglar, D.T., Giessen, T.W., Baym, M., Kerns, S.J., Niederhuber, M.J., Bronson, R.T., Kotula, J.W., Gerber, G.K., Way, J.C., Silver, P.A. 2017. Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation. Nature Biotechnology.
  10. Kimizuka, Y., Callahan, J.J., Huang, Z., Morse, K., Katagiri, W., Shigeta, A., Bronson, R., Takeuchi, S., Shimaoka, Y., Chan, M.P.K., Zeng, Y., Li, B., Chen, H., Tan, R.Y.Y., Dwyer, C., Mulley, T., Leblanc, P., Goudie, C., Gelfand, J., Tsukada, K., Brauns, T., Poznansky, M.C., Bean, D., Kashiwagi, S. 2017. Semiconductor diode laser device adjuvanting intradermal vaccine. Vaccine.
  11. Wan, L., Chen, M., Cao, J., Dai, X., Yin, Q., Zhang, J., Song, S.-J., Lu, Y., Liu, J., Inuzuka, H., Katon, J.M., Berry, K., Fung, J., Ng, C., Liu, P., Song, M.S., Xue, L., Bronson, R.T., Kirschner, M.W., Cui, R., Pandolfi, P.P., Wei, W. 2017. The APC/C E3 ligase complex activator fzr1 restricts braf oncogenic function. Cancer Discovery.
  12. Foijer, F., Albacker, L.A., Bakker, B., Spierings, D.C., Yue, Y., Xie, S.Z., Davis, S., Lutum-Jehle, A., Takemoto, D., Hare, B., Furey, B., Bronson, R.T., Lansdorp, P.M., Bradley, A., Sorger, P.K. 2017. Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma. eLife.
  13. Guerriero, J.L., Sotayo, A., Ponichtera, H.E., Castrillon, J.A., Pourzia, A.L., Schad, S., Johnson, S.F., Carrasco, R.D., Lazo, S., Bronson, R.T., Davis, S.P., Lobera, M., Nolan, M.A., Letai, A. 2017. Class IIa HDAC inhibition reduces breast tumours and metastases through anti-tumour macrophages. Nature.
  14. Fan, Y., Hanai, J.-I., Le, P.T., Bi, R., Maridas, D., DeMambro, V., Figueroa, C.A., Kir, S., Zhou, X., Mannstadt, M., Baron, R., Bronson, R.T., Horowitz, M.C., Wu, J.Y., Bilezikian, J.P., Dempster, D.W., Rosen, C.J., Lanske, B. 2017. Parathyroid Hormone Directs Bone Marrow Mesenchymal Cell Fate. Cell Metabolism.
  15. Liu, L., Michowski, W., Inuzuka, H., Shimizu, K., Nihira, N.T., Chick, J.M., Li, N., Geng, Y., Meng, A.Y., Ordureau, A., Kołodziejczyk, A., Ligon, K.L., Bronson, R.T., Polyak, K., Harper, J.W., Gygi, S.P., Wei, W., Sicinski, P. 2017. G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells. Nature Cell Biology.
  16. Tao, L., Xiang, D., Xie, Y., Bronson, R.T., Li, Z. 2017. Induced p53 loss in mouse luminal cells causes clonal expansion and development of mammary tumours. Nature Communications.
  17. Kang, Y.-J., Balter, B., Csizmadia, E., Haas, B., Sharma, H., Bronson, R., Yan, C.T. 2017. Contribution of classical end-joining to PTEN inactivation in p53-mediated glioblastoma formation and drug-resistant survival. Nature Communications.
  18. Ferrés, M.A., Bianchi, D.W., Siegel, A.E., Bronson, R.T., Huggins, G.S., Guedj, F. 2016. Perinatal natural history of the Ts1Cje mouse model of down syndrome: Growth restriction, early mortality, heart defects, and delayed development. PLoS ONE.
  19. Duran-Struuck, R., Matar, A.J., Crepeau, R.L., Teague, A.G.S., Horner, B.M., Pathiraja, V., Spitzer, T.R., Fishman, J.A., Bronson, R.T., Sachs, D.H., Huang, C.A. 2016. Donor Lymphocyte Infusion–Mediated Graft-versus-Host Responses in a Preclinical Swine Model of Haploidentical Hematopoietic Cell Transplantation. Biology of Blood and Marrow Transplantation.
  20. McFadden, D.G., Politi, K., Bhutkar, A., Chen, F.K., Song, X., Pirun, M., Santiago, P.M., Kim-Kiselak, C., Platt, J.T., Lee, E., Hodges, E., Rosebrock, A.P., Bronson, R.T., Socci, N.D., Hannon, G.J., Jacks, T., Varmus, H. 2016. Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma. Proceedings of the National Academy of Sciences of the United States of America.

General Research Interests

  • Pathology of mutant mice
  • Pathology of aging
  • Cancer pathobiology

Research Interests by Area

Other Areas of Research
  • Mutant Mouse pathology