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Roderick T. Bronson - DVM, BA

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Professor
Pathology, Markers of Aging
Pathology

Campus Phone:
617-432-2409

Education

  • DVM - University of California, Davis - 1972
  • BA - University of California, Berkeley - 1964

Board Certification

  • American College of Veterinary Pathology
  1. Jun, H.J., Appleman, V.A., Wu, H.-J., Rose, C.M., Pineda, J.J., Yeo, A.T., Delcuze, B., Lee, C., Gyuris, A., Zhu, H., Woolfenden, S., Bronisz, A., Nakano, I., Chiocca, E.A., Bronson, R.T., Ligon, K.L., Sarkaria, J.N., Gygi, S.P., Michor, F., Mitchison, T.J., Charest, A. 2018. A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine. Nature Communications.
  2. Qin, Y., Garrison, B.S., Ma, W., Wang, R., Jiang, A., Li, J., Mistry, M., Bronson, R.T., Santoro, D., Franco, C., Robinton, D.A., Stevens, B., Rossi, D.J., Lu, C., Springer, T.A. 2018. A Milieu Molecule for TGF-β Required for Microglia Function in the Nervous System. Cell.
  3. Takahashi, N., Chen, H.-Y., Harris, I.S., Stover, D.G., Selfors, L.M., Bronson, R.T., Deraedt, T., Cichowski, K., Welm, A.L., Mori, Y., Mills, G.B., Brugge, J.S. 2018. Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance. Cancer Cell.
  4. Martinot, A.J., Abbink, P., Afacan, O., Prohl, A.K., Bronson, R., Hecht, J.L., Borducchi, E.N., Larocca, R.A., Peterson, R.L., Rinaldi, W., Ferguson, M., Didier, P.J., Weiss, D., Lewis, M.G., De La Barrera, R.A., Yang, E., Warfield, S.K., Barouch, D.H. 2018. Fetal Neuropathology in Zika Virus-Infected Pregnant Female Rhesus Monkeys. Cell.
  5. Xu, H., Lee, M.-S., Tsai, P.-Y., Adler, A.S., Curry, N.L., Challa, S., Freinkman, E., Hitchcock, D.S., Copps, K.D., White, M.F., Bronson, R.T., Marcotrigiano, M., Wu, Y., Clish, C.B., Kalaany, N.Y. 2018. Ablation of insulin receptor substrates 1 and 2 suppresses Kras-driven lung tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America.
  6. McBrayer, S.K., Olenchock, B.A., DiNatale, G.J., Shi, D.D., Khanal, J., Jennings, R.B., Novak, J.S., Oser, M.G., Robbins, A.K., Modiste, R., Bonal, D., Moslehi, J., Bronson, R.T., Neuberg, D., Nguyen, Q.-D., Signoretti, S., Losman, J.-A., Kaelin, W.G. 2018. Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase. Proceedings of the National Academy of Sciences of the United States of America.
  7. Albertsson, A.-M., Zhang, X., Vontell, R., Bi, D., Bronson, R.T., Supramaniam, V., Baburamani, A.A., Hua, S., Nazmi, A., Cardell, S., Zhu, C., Cantor, H., Mallard, C., Hagberg, H., Leavenworth, J.W., Wang, X. 2018. γδ T Cells Contribute to Injury in the Developing Brain. American Journal of Pathology.
  8. Hwang, I., Oh, H., Santo, E., Kim, D.-Y., Chen, J.W., Bronson, R.T., Locasale, J.W., Na, Y., Lee, J., Reed, S., Toth, M., Yu, W.H., Muller, F.L., Paik, J. 2018. FOXO protects against age-progressive axonal degeneration. Aging Cell.
  9. Chen, M., Zhang, J., Sampieri, K., Clohessy, J.G., Mendez, L., Gonzalez-Billalabeitia, E., Liu, X.-S., Lee, Y.-R., Fung, J., Katon, J.M., Menon, A.V., Webster, K.A., Ng, C., Palumbieri, M.D., Diolombi, M.S., Breitkopf, S.B., Teruya-Feldstein, J., Signoretti, S., Bronson, R.T., Asara, J.M., Castillo-Martin, M., Cordon-Cardo, C., Pandolfi, P.P. 2018. An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer. Nature Genetics.
  10. Geng, Y., Michowski, W., Chick, J.M., Wang, Y.E., Emmanuelle Jecrois, M., Sweeney, K.E., Liu, L., Han, R.C., Ke, N., Zagozdzon, A., Sicinska, E., Bronson, R.T., Gygi, S.P., Sicinski, P. 2018. Kinase-independent function of E-type cyclins in liver cancer. Proceedings of the National Academy of Sciences of the United States of America.
  11. Zoeller, J.J., Bronson, R.T., Selfors, L.M., Mills, G.B., Brugge, J.S. 2017. Niche-localized tumor cells are protected from HER2-targeted therapy via upregulation of an anti-apoptotic program in vivo. npj Breast Cancer.
  12. Lee, S.-G., Mikhalchenko, A.E., Yim, S.H., Lobanov, A.V., Park, J.-K., Choi, K.-H., Bronson, R.T., Lee, C.-K., Park, T.J., Gladyshev, V.N. 2017. Naked Mole Rat Induced Pluripotent Stem Cells and Their Contribution to Interspecific Chimera. Stem Cell Reports.
  13. Romero, R., Sayin, V.I., Davidson, S.M., Bauer, M.R., Singh, S.X., Leboeuf, S.E., Karakousi, T.R., Ellis, D.C., Bhutkar, A., Sánchez-Rivera, F.J., Subbaraj, L., Martinez, B., Bronson, R.T., Prigge, J.R., Schmidt, E.E., Thomas, C.J., Goparaju, C., Davies, A., Dolgalev, I., Heguy, A., Allaj, V., Poirier, J.T., Moreira, A.L., Rudin, C.M., Pass, H.I., Vander Heiden, M.G., Jacks, T., Papagiannakopoulos, T. 2017. Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis. Nature Medicine.
  14. Otto, T., Candido, S.V., Pilarz, M.S., Sicinska, E., Bronson, R.T., Bowden, M., Lachowicz, I.A., Mulry, K., Fassl, A., Han, R.C., Jecrois, E.S., Sicinski, P. 2017. Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proceedings of the National Academy of Sciences of the United States of America.
  15. Wang, Z., Zheng, Q., Zhang, H., Bronson, R.T., Madsen, J.C., Sachs, D.H., Huang, C.A., Wang, Z. 2017. Ontak-like human IL-2 fusion toxin. Journal of Immunological Methods.
  16. Morse, K., Kimizuka, Y., Chan, M.P.K., Shibata, M., Shimaoka, Y., Takeuchi, S., Forbes, B., Nirschl, C., Li, B., Zeng, Y., Bronson, R.T., Katagiri, W., Shigeta, A., Srbulescu, R.F., Chen, H., Tan, R.Y.Y., Tsukada, K., Brauns, T., Gelfand, J., Sluder, A., Locascio, J.J., Poznansky, M.C., Anandasabapathy, N., Kashiwagi, S. 2017. Near-infrared 1064 nm laser modulates migratory dendritic cells to augment the immune response to intradermal influenza vaccine. Journal of Immunology.
  17. Jordan, J.J., Chhim, S., Margulies, C.M., Allocca, M., Bronson, R.T., Klungland, A., Samson, L.D., Fu, D. 2017. ALKBH7 drives a tissue and sex-specific necrotic cell death response following alkylation-induced damage. Cell death & disease.
  18. Riglar, D.T., Giessen, T.W., Baym, M., Kerns, S.J., Niederhuber, M.J., Bronson, R.T., Kotula, J.W., Gerber, G.K., Way, J.C., Silver, P.A. 2017. Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation. Nature Biotechnology.
  19. Kimizuka, Y., Callahan, J.J., Huang, Z., Morse, K., Katagiri, W., Shigeta, A., Bronson, R., Takeuchi, S., Shimaoka, Y., Chan, M.P.K., Zeng, Y., Li, B., Chen, H., Tan, R.Y.Y., Dwyer, C., Mulley, T., Leblanc, P., Goudie, C., Gelfand, J., Tsukada, K., Brauns, T., Poznansky, M.C., Bean, D., Kashiwagi, S. 2017. Semiconductor diode laser device adjuvanting intradermal vaccine. Vaccine.
  20. Wan, L., Chen, M., Cao, J., Dai, X., Yin, Q., Zhang, J., Song, S.-J., Lu, Y., Liu, J., Inuzuka, H., Katon, J.M., Berry, K., Fung, J., Ng, C., Liu, P., Song, M.S., Xue, L., Bronson, R.T., Kirschner, M.W., Cui, R., Pandolfi, P.P., Wei, W. 2017. The APC/C E3 ligase complex activator fzr1 restricts braf oncogenic function. Cancer Discovery.

General Research Interests

  • Pathology of mutant mice
  • Pathology of aging
  • Cancer pathobiology

Research Interests by Area

Other Areas of Research
  • Mutant Mouse pathology