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Roderick T. Bronson - DVM, BA

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Pathology, Markers of Aging

Campus Phone:


  • DVM - University of California, Davis - 1972
  • BA - University of California, Berkeley - 1964

Board Certification

  • American College of Veterinary Pathology
  1. Barros-Silva, J.D., Linn, D.E., Steiner, I., Guo, G., Ali, A., Pakula, H., Ashton, G., Peset, I., Brown, M., Clarke, N.W., Bronson, R.T., Yuan, G.-C., Orkin, S.H., Li, Z., Baena, E. 2018. Single-Cell Analysis Identifies LY6D as a Marker Linking Castration-Resistant Prostate Luminal Cells to Prostate Progenitors and Cancer. Cell Reports.
  2. Ding, L., Kim, H.-J., Wang, Q., Kearns, M., Jiang, T., Ohlson, C.E., Li, B.B., Xie, S., Liu, J.F., Stover, E.H., Howitt, B.E., Bronson, R.T., Lazo, S., Roberts, T.M., Freeman, G.J., Konstantinopoulos, P.A., Matulonis, U.A., Zhao, J.J. 2018. PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer. Cell Reports.
  3. Dischinger, P.S., Tovar, E.A., Essenburg, C.J., Madaj, Z.B., Gardner, E.E., Callaghan, M.E., Turner, A.N., Challa, A.K., Kempston, T., Eagleson, B., Kesterson, R.A., Bronson, R.T., Bowman, M.J., Graveel, C.R., Steensma, M.R. 2018. NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer. npj Breast Cancer.
  4. Jun, H.J., Appleman, V.A., Wu, H.-J., Rose, C.M., Pineda, J.J., Yeo, A.T., Delcuze, B., Lee, C., Gyuris, A., Zhu, H., Woolfenden, S., Bronisz, A., Nakano, I., Chiocca, E.A., Bronson, R.T., Ligon, K.L., Sarkaria, J.N., Gygi, S.P., Michor, F., Mitchison, T.J., Charest, A. 2018. A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine. Nature Communications.
  5. Chang, A.N., Liang, Z., Dai, H.-Q., Chapdelaine-Williams, A.M., Andrews, N., Bronson, R.T., Schwer, B., Alt, F.W. 2018. Neural blastocyst complementation enables mouse forebrain organogenesis. Nature.
  6. Li, A.G., Murphy, E.C., Culhane, A.C., Powell, E., Wang, H., Bronson, R.T., Von, T., Giobbie-Hurder, A., Gelman, R.S., Briggs, K.J., Piwnica-Worms, H., Zhao, J.J., Kung, A.L., Kaelin, W.G., Livingston, D.M. 2018. BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation. Proceedings of the National Academy of Sciences of the United States of America.
  7. Sinkevicius, K.W., Bellaria, K.J., Barrios, J., Pessina, P., Gupta, M., Brainson, C.F., Bronson, R.T., Kim, C.F. 2018. E-cadherin loss accelerates tumor progression and metastasis in a mouse model of lung adenocarcinoma. American Journal of Respiratory Cell and Molecular Biology.
  8. Qin, Y., Garrison, B.S., Ma, W., Wang, R., Jiang, A., Li, J., Mistry, M., Bronson, R.T., Santoro, D., Franco, C., Robinton, D.A., Stevens, B., Rossi, D.J., Lu, C., Springer, T.A. 2018. A Milieu Molecule for TGF-β Required for Microglia Function in the Nervous System. Cell.
  9. Takahashi, N., Chen, H.-Y., Harris, I.S., Stover, D.G., Selfors, L.M., Bronson, R.T., Deraedt, T., Cichowski, K., Welm, A.L., Mori, Y., Mills, G.B., Brugge, J.S. 2018. Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance. Cancer Cell.
  10. Martinot, A.J., Abbink, P., Afacan, O., Prohl, A.K., Bronson, R., Hecht, J.L., Borducchi, E.N., Larocca, R.A., Peterson, R.L., Rinaldi, W., Ferguson, M., Didier, P.J., Weiss, D., Lewis, M.G., De La Barrera, R.A., Yang, E., Warfield, S.K., Barouch, D.H. 2018. Fetal Neuropathology in Zika Virus-Infected Pregnant Female Rhesus Monkeys. Cell.
  11. Xu, H., Lee, M.-S., Tsai, P.-Y., Adler, A.S., Curry, N.L., Challa, S., Freinkman, E., Hitchcock, D.S., Copps, K.D., White, M.F., Bronson, R.T., Marcotrigiano, M., Wu, Y., Clish, C.B., Kalaany, N.Y. 2018. Ablation of insulin receptor substrates 1 and 2 suppresses Kras-driven lung tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America.
  12. McBrayer, S.K., Olenchock, B.A., DiNatale, G.J., Shi, D.D., Khanal, J., Jennings, R.B., Novak, J.S., Oser, M.G., Robbins, A.K., Modiste, R., Bonal, D., Moslehi, J., Bronson, R.T., Neuberg, D., Nguyen, Q.-D., Signoretti, S., Losman, J.-A., Kaelin, W.G. 2018. Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase. Proceedings of the National Academy of Sciences of the United States of America.
  13. Albertsson, A.-M., Zhang, X., Vontell, R., Bi, D., Bronson, R.T., Supramaniam, V., Baburamani, A.A., Hua, S., Nazmi, A., Cardell, S., Zhu, C., Cantor, H., Mallard, C., Hagberg, H., Leavenworth, J.W., Wang, X. 2018. γδ T Cells Contribute to Injury in the Developing Brain. American Journal of Pathology.
  14. Hwang, I., Oh, H., Santo, E., Kim, D.-Y., Chen, J.W., Bronson, R.T., Locasale, J.W., Na, Y., Lee, J., Reed, S., Toth, M., Yu, W.H., Muller, F.L., Paik, J. 2018. FOXO protects against age-progressive axonal degeneration. Aging Cell.
  15. Chen, M., Zhang, J., Sampieri, K., Clohessy, J.G., Mendez, L., Gonzalez-Billalabeitia, E., Liu, X.-S., Lee, Y.-R., Fung, J., Katon, J.M., Menon, A.V., Webster, K.A., Ng, C., Palumbieri, M.D., Diolombi, M.S., Breitkopf, S.B., Teruya-Feldstein, J., Signoretti, S., Bronson, R.T., Asara, J.M., Castillo-Martin, M., Cordon-Cardo, C., Pandolfi, P.P. 2018. An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer. Nature Genetics.
  16. Geng, Y., Michowski, W., Chick, J.M., Wang, Y.E., Emmanuelle Jecrois, M., Sweeney, K.E., Liu, L., Han, R.C., Ke, N., Zagozdzon, A., Sicinska, E., Bronson, R.T., Gygi, S.P., Sicinski, P. 2018. Kinase-independent function of E-type cyclins in liver cancer. Proceedings of the National Academy of Sciences of the United States of America.
  17. Zhou, S., Appleman, V.A., Rose, C.M., Jun, H.J., Yang, J., Zhou, Y., Bronson, R.T., Gygi, S.P., Charest, A. 2018. Chronic platelet-derived growth factor receptor signaling exerts control over initiation of protein translation in glioma. Life Science Alliance.
  18. Zoeller, J.J., Bronson, R.T., Selfors, L.M., Mills, G.B., Brugge, J.S. 2017. Niche-localized tumor cells are protected from HER2-targeted therapy via upregulation of an anti-apoptotic program in vivo. npj Breast Cancer.
  19. Lee, S.-G., Mikhalchenko, A.E., Yim, S.H., Lobanov, A.V., Park, J.-K., Choi, K.-H., Bronson, R.T., Lee, C.-K., Park, T.J., Gladyshev, V.N. 2017. Naked Mole Rat Induced Pluripotent Stem Cells and Their Contribution to Interspecific Chimera. Stem Cell Reports.
  20. Romero, R., Sayin, V.I., Davidson, S.M., Bauer, M.R., Singh, S.X., Leboeuf, S.E., Karakousi, T.R., Ellis, D.C., Bhutkar, A., Sánchez-Rivera, F.J., Subbaraj, L., Martinez, B., Bronson, R.T., Prigge, J.R., Schmidt, E.E., Thomas, C.J., Goparaju, C., Davies, A., Dolgalev, I., Heguy, A., Allaj, V., Poirier, J.T., Moreira, A.L., Rudin, C.M., Pass, H.I., Vander Heiden, M.G., Jacks, T., Papagiannakopoulos, T. 2017. Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis. Nature Medicine.

General Research Interests

  • Pathology of mutant mice
  • Pathology of aging
  • Cancer pathobiology

Research Interests by Area

Other Areas of Research
  • Mutant Mouse pathology