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Roderick T. Bronson - DVM, BA

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Pathology, Markers of Aging

Campus Phone:


  • DVM - University of California, Davis - 1972
  • BA - University of California, Berkeley - 1964

Board Certification

  • American College of Veterinary Pathology
  1. Mattaini, K.R., Sullivan, M.R., Lau, A.N., Fiske, B.P., Bronson, R.T., Heiden, M.G.V. 2019. Increased PHGDH expression promotes aberrant melanin accumulation. BMC Cancer.
  2. Lesch, B.J., Tothova, Z., Morgan, E.A., Liao, Z., Bronson, R.T., Ebert, B.L., Page, D.C. 2019. Intergenerational epigenetic inheritance of cancer susceptibility in mammals. eLife.
  3. Wu, X., Koh, G.Y., Huang, Y., Crott, J.W., Bronson, R.T., Mason, J.B. 2019. The Combination of Curcumin and Salsalate is Superior to Either Agent Alone in Suppressing Pro-Cancerous Molecular Pathways and Colorectal Tumorigenesis in Obese Mice. Molecular Nutrition and Food Research.
  4. Chen, M., Zhang, J., Berger, A.H., Diolombi, M.S., Ng, C., Fung, J., Bronson, R.T., Castillo-Martin, M., Thin, T.H., Cordon-Cardo, C., Plevin, R., Pandolfi, P.P. 2019. Compound haploinsufficiency of Dok2 and Dusp4 promotes lung tumorigenesis. Journal of Clinical Investigation.
  5. Gluchowski, N.L., Gabriel, K.R., Chitraju, C., Bronson, R.T., Mejhert, N., Boland, S., Wang, K., Lai, Z.W., Farese, R.V., Walther, T.C. 2019. Hepatocyte Deletion of Triglyceride-Synthesis Enzyme Acyl CoA: Diacylglycerol Acyltransferase 2 Reduces Steatosis Without Increasing Inflammation or Fibrosis in Mice. Hepatology.
  6. Zoeller, J.J., Vagodny, A., Taneja, K., Tan, B.Y., O'Brien, N., Slamon, D.J., Sampath, D., Leverson, J.D., Bronson, R.T., Dillon, D.A., Brugge, J.S. 2019. Neutralization of Bcl-2/XL enhances the cytotoxicity of T-DM1 in vivo. Molecular Cancer Therapeutics.
  7. Barros-Silva, J.D., Linn, D.E., Steiner, I., Guo, G., Ali, A., Pakula, H., Ashton, G., Peset, I., Brown, M., Clarke, N.W., Bronson, R.T., Yuan, G.-C., Orkin, S.H., Li, Z., Baena, E. 2018. Single-Cell Analysis Identifies LY6D as a Marker Linking Castration-Resistant Prostate Luminal Cells to Prostate Progenitors and Cancer. Cell Reports.
  8. Du, H., Dreier, J.R., Zarei, M., Wu, C.-L., Bronson, R.W., Kwiatkowski, D.J. 2018. A novel mouse model of hemangiopericytoma due to loss of Tsc2. Human molecular genetics.
  9. Ding, L., Kim, H.-J., Wang, Q., Kearns, M., Jiang, T., Ohlson, C.E., Li, B.B., Xie, S., Liu, J.F., Stover, E.H., Howitt, B.E., Bronson, R.T., Lazo, S., Roberts, T.M., Freeman, G.J., Konstantinopoulos, P.A., Matulonis, U.A., Zhao, J.J. 2018. PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer. Cell Reports.
  10. Santana-Codina, N., Roeth, A.A., Zhang, Y., Yang, A., Mashadova, O., Asara, J.M., Wang, X., Bronson, R.T., Lyssiotis, C.A., Ying, H., Kimmelman, A.C. 2018. Oncogenic KRAS supports pancreatic cancer through regulation of nucleotide synthesis. Nature Communications.
  11. Dischinger, P.S., Tovar, E.A., Essenburg, C.J., Madaj, Z.B., Gardner, E.E., Callaghan, M.E., Turner, A.N., Challa, A.K., Kempston, T., Eagleson, B., Kesterson, R.A., Bronson, R.T., Bowman, M.J., Graveel, C.R., Steensma, M.R. 2018. NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer. npj Breast Cancer.
  12. Jun, H.J., Appleman, V.A., Wu, H.-J., Rose, C.M., Pineda, J.J., Yeo, A.T., Delcuze, B., Lee, C., Gyuris, A., Zhu, H., Woolfenden, S., Bronisz, A., Nakano, I., Chiocca, E.A., Bronson, R.T., Ligon, K.L., Sarkaria, J.N., Gygi, S.P., Michor, F., Mitchison, T.J., Charest, A. 2018. A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine. Nature Communications.
  13. Chang, A.N., Liang, Z., Dai, H.-Q., Chapdelaine-Williams, A.M., Andrews, N., Bronson, R.T., Schwer, B., Alt, F.W. 2018. Neural blastocyst complementation enables mouse forebrain organogenesis. Nature.
  14. Li, A.G., Murphy, E.C., Culhane, A.C., Powell, E., Wang, H., Bronson, R.T., Von, T., Giobbie-Hurder, A., Gelman, R.S., Briggs, K.J., Piwnica-Worms, H., Zhao, J.J., Kung, A.L., Kaelin, W.G., Livingston, D.M. 2018. BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation. Proceedings of the National Academy of Sciences of the United States of America.
  15. Vijayakumar, V., Vanhove, A.S., Pickering, B.S., Liao, J., Tierney, B.T., Asara, J.M., Bronson, R., Watnick, P.I. 2018. Removal of a membrane anchor reveals the opposing regulatory functions of Vibrio cholerae glucose-specific enzyme IIA in biofilms and the mammalian intestine. mBio.
  16. Sinkevicius, K.W., Bellaria, K.J., Barrios, J., Pessina, P., Gupta, M., Brainson, C.F., Bronson, R.T., Kim, C.F. 2018. E-cadherin loss accelerates tumor progression and metastasis in a mouse model of lung adenocarcinoma. American Journal of Respiratory Cell and Molecular Biology.
  17. Qin, Y., Garrison, B.S., Ma, W., Wang, R., Jiang, A., Li, J., Mistry, M., Bronson, R.T., Santoro, D., Franco, C., Robinton, D.A., Stevens, B., Rossi, D.J., Lu, C., Springer, T.A. 2018. A Milieu Molecule for TGF-β Required for Microglia Function in the Nervous System. Cell.
  18. Panchamoorthy, G., Jin, C., Raina, D., Bharti, A., Yamamoto, M., Adeebge, D., Zhao, Q., Bronson, R., Jiang, S., Li, L., Suzuki, Y., Tagde, A., Ghoroghchian, P.P., Wong, K.-K., Kharbanda, S., Kufe, D. 2018. Targeting the human MUC1-C oncoprotein with an antibody-drug conjugate. JCI insight.
  19. Takahashi, N., Chen, H.-Y., Harris, I.S., Stover, D.G., Selfors, L.M., Bronson, R.T., Deraedt, T., Cichowski, K., Welm, A.L., Mori, Y., Mills, G.B., Brugge, J.S. 2018. Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance. Cancer Cell.
  20. Martinot, A.J., Abbink, P., Afacan, O., Prohl, A.K., Bronson, R., Hecht, J.L., Borducchi, E.N., Larocca, R.A., Peterson, R.L., Rinaldi, W., Ferguson, M., Didier, P.J., Weiss, D., Lewis, M.G., De La Barrera, R.A., Yang, E., Warfield, S.K., Barouch, D.H. 2018. Fetal Neuropathology in Zika Virus-Infected Pregnant Female Rhesus Monkeys. Cell.

General Research Interests

  • Pathology of mutant mice
  • Pathology of aging
  • Cancer pathobiology

Research Interests by Area

Other Areas of Research
  • Mutant Mouse pathology