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Roderick T. Bronson - DVM, BA

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Professor
Pathology, Markers of Aging
Pathology

Campus Phone:
617-432-2409

Education

  • DVM - University of California, Davis - 1972
  • BA - University of California, Berkeley - 1964

Board Certification

  • American College of Veterinary Pathology
  1. Prabhakar, S., Cheah, P.S., Zhang, X., Zinter, M., Gianatasio, M., Hudry, E., Bronson, R.T., Kwiatkowski, D.J., Stemmer-Rachamimov, A., Maguire, C.A., Sena-Esteves, M., Tannous, B.A., Breakefield, X.O. 2019. Long-Term Therapeutic Efficacy of Intravenous AAV-Mediated Hamartin Replacement in Mouse Model of Tuberous Sclerosis Type 1. Molecular Therapy - Methods and Clinical Development.
  2. Mukherjee, P., Augur, Z.M., Li, M., Hill, C., Greenwood, B., Domin, M.A., Kondakci, G., Narain, N.R., Kiebish, M.A., Bronson, R.T., Arismendi-Morillo, G., Chinopoulos, C., Seyfried, T.N. 2019. Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-stage experimental glioblastoma. Communications Biology.
  3. Wang, B., Li, D., Yao, Y., Heyns, M., Kovalchuk, A., Ilnytskyy, Y., Rodriguez-Juarez, R., Bronson, R.T., Metz, G.A.S., Kovalchuk, O., Kovalchuk, I. 2019. The crucial role of DNA-dependent protein kinase and myelin transcription factor 1-like protein in the miR-141 tumor suppressor network. Cell Cycle.
  4. Mattaini, K.R., Sullivan, M.R., Lau, A.N., Fiske, B.P., Bronson, R.T., Heiden, M.G.V. 2019. Increased PHGDH expression promotes aberrant melanin accumulation. BMC Cancer.
  5. Wu, X., Koh, G.Y., Huang, Y., Crott, J.W., Bronson, R.T., Mason, J.B. 2019. The Combination of Curcumin and Salsalate is Superior to Either Agent Alone in Suppressing Pro-Cancerous Molecular Pathways and Colorectal Tumorigenesis in Obese Mice. Molecular Nutrition and Food Research.
  6. Chen, M., Zhang, J., Berger, A.H., Diolombi, M.S., Ng, C., Fung, J., Bronson, R.T., Castillo-Martin, M., Thin, T.H., Cordon-Cardo, C., Plevin, R., Pandolfi, P.P. 2019. Compound haploinsufficiency of Dok2 and Dusp4 promotes lung tumorigenesis. Journal of Clinical Investigation.
  7. Lesch, B.J., Tothova, Z., Morgan, E.A., Liao, Z., Bronson, R.T., Ebert, B.L., Page, D.C. 2019. Intergenerational epigenetic inheritance of cancer susceptibility in mammals. eLife.
  8. Nelson, D.S., Marano, R.L., Joo, Y., Tian, S.Y., Patel, B., Kaplan, D.H., Shlomchik, M.J., Stevenson, K., Bronson, R.T., Rollins, B.J. 2019. BRAF V600E and Pten deletion in mice produces a histiocytic disorder with features of Langerhans cell histiocytosis. PLoS ONE.
  9. Zoeller, J.J., Vagodny, A., Taneja, K., Tan, B.Y., O'Brien, N., Slamon, D.J., Sampath, D., Leverson, J.D., Bronson, R.T., Dillon, D.A., Brugge, J.S. 2019. Neutralization of Bcl-2/XL enhances the cytotoxicity of T-DM1 in vivo. Molecular Cancer Therapeutics.
  10. Barros-Silva, J.D., Linn, D.E., Steiner, I., Guo, G., Ali, A., Pakula, H., Ashton, G., Peset, I., Brown, M., Clarke, N.W., Bronson, R.T., Yuan, G.-C., Orkin, S.H., Li, Z., Baena, E. 2018. Single-Cell Analysis Identifies LY6D as a Marker Linking Castration-Resistant Prostate Luminal Cells to Prostate Progenitors and Cancer. Cell Reports.
  11. Du, H., Dreier, J.R., Zarei, M., Wu, C.-L., Bronson, R.W., Kwiatkowski, D.J. 2018. A novel mouse model of hemangiopericytoma due to loss of Tsc2. Human molecular genetics.
  12. Ding, L., Kim, H.-J., Wang, Q., Kearns, M., Jiang, T., Ohlson, C.E., Li, B.B., Xie, S., Liu, J.F., Stover, E.H., Howitt, B.E., Bronson, R.T., Lazo, S., Roberts, T.M., Freeman, G.J., Konstantinopoulos, P.A., Matulonis, U.A., Zhao, J.J. 2018. PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer. Cell Reports.
  13. Santana-Codina, N., Roeth, A.A., Zhang, Y., Yang, A., Mashadova, O., Asara, J.M., Wang, X., Bronson, R.T., Lyssiotis, C.A., Ying, H., Kimmelman, A.C. 2018. Oncogenic KRAS supports pancreatic cancer through regulation of nucleotide synthesis. Nature Communications.
  14. Dischinger, P.S., Tovar, E.A., Essenburg, C.J., Madaj, Z.B., Gardner, E.E., Callaghan, M.E., Turner, A.N., Challa, A.K., Kempston, T., Eagleson, B., Kesterson, R.A., Bronson, R.T., Bowman, M.J., Graveel, C.R., Steensma, M.R. 2018. NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer. npj Breast Cancer.
  15. Jun, H.J., Appleman, V.A., Wu, H.-J., Rose, C.M., Pineda, J.J., Yeo, A.T., Delcuze, B., Lee, C., Gyuris, A., Zhu, H., Woolfenden, S., Bronisz, A., Nakano, I., Chiocca, E.A., Bronson, R.T., Ligon, K.L., Sarkaria, J.N., Gygi, S.P., Michor, F., Mitchison, T.J., Charest, A. 2018. A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine. Nature Communications.
  16. Chang, A.N., Liang, Z., Dai, H.-Q., Chapdelaine-Williams, A.M., Andrews, N., Bronson, R.T., Schwer, B., Alt, F.W. 2018. Neural blastocyst complementation enables mouse forebrain organogenesis. Nature.
  17. Li, A.G., Murphy, E.C., Culhane, A.C., Powell, E., Wang, H., Bronson, R.T., Von, T., Giobbie-Hurder, A., Gelman, R.S., Briggs, K.J., Piwnica-Worms, H., Zhao, J.J., Kung, A.L., Kaelin, W.G., Livingston, D.M. 2018. BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation. Proceedings of the National Academy of Sciences of the United States of America.
  18. Vijayakumar, V., Vanhove, A.S., Pickering, B.S., Liao, J., Tierney, B.T., Asara, J.M., Bronson, R., Watnick, P.I. 2018. Removal of a membrane anchor reveals the opposing regulatory functions of Vibrio cholerae glucose-specific enzyme IIA in biofilms and the mammalian intestine. mBio.
  19. Sinkevicius, K.W., Bellaria, K.J., Barrios, J., Pessina, P., Gupta, M., Brainson, C.F., Bronson, R.T., Kim, C.F. 2018. E-cadherin loss accelerates tumor progression and metastasis in a mouse model of lung adenocarcinoma. American Journal of Respiratory Cell and Molecular Biology.
  20. Qin, Y., Garrison, B.S., Ma, W., Wang, R., Jiang, A., Li, J., Mistry, M., Bronson, R.T., Santoro, D., Franco, C., Robinton, D.A., Stevens, B., Rossi, D.J., Lu, C., Springer, T.A. 2018. A Milieu Molecule for TGF-β Required for Microglia Function in the Nervous System. Cell.

General Research Interests

  • Pathology of mutant mice
  • Pathology of aging
  • Cancer pathobiology

Research Interests by Area

Other Areas of Research
  • Mutant Mouse pathology