Open Menu Close Menu Open Search Close Search Open Directory Close Directory

Phyllis Mann

Phyllis Mann
Associate Professor
Section of Neuroscience and Reproductive Biology

Campus Phone:



  • PhD - City University of New York -1987
  • MA - Queens College - 1985
  • BA - Queens College - 1973
  1. Nephew, B.C., Nemeth, A., Hudda, N., Beamer, G., Mann, P., Petitto, J., Cali, R., Febo, M., Kulkarni, P., Poirier, G., King, J., Durant, J.L., Brugge, D. 2020. Traffic-related particulate matter affects behavior, inflammation, and neural integrity in a developmental rodent model. Environmental Research.
  2. Hudda, N., Durant, J.L., Nemeth, A., Mann, P., Petitto, J., Brugge, D., Nephew, B.C. 2019. Bedding-generated particulate matter: implications for rodent studies. Inhalation Toxicology.
  3. Mann, P.E., Huynh, K., Widmer, G. 2018. Maternal high fat diet and its consequence on the gut microbiome: A rat model. Gut Microbes.
  4. Mazor-Thomas, J.E., Mann, P.E., Karas, A.Z., Tseng, F. 2014. Pain-suppressed behaviors in the red-tailed hawk (Buteo jamaicensis). Applied Animal Behaviour Science.
  5. Mann, P.E. 2014. Gene expression profiling during pregnancy in rat brain tissue. Brain Sciences.
  6. Mann, P.E., Gervais, K.J. 2011. Environmental enrichment delays pup-induced maternal behavior in rats. Developmental Psychobiology.
  7. Mann, P.E. 2006. Finasteride delays the onset of maternal behavior in primigravid rats. Physiology and Behavior.
  8. Mann, P.E., Babb, J.A. 2005. Neural steroid hormone receptor gene expression in pregnant rats. Molecular Brain Research.
  9. Mann, P.E., Babb, J.A. 2004. Disinhibition of maternal behavior following neurotoxic lesions of the hypothalamus in primigravid rats. Brain Research.
  10. Mann, P.E., Bridges, R.S. 2002. Prolactin receptor gene expression in the forebrain of pregnant and lactating rats. Molecular Brain Research.
  11. Mann, P.E., Bridges, R.S. 2001. Lactogenic hormone regulation of maternal behavior. Progress in Brain Research.
  12. Gulledge, C.C., Mann, P.E., Bridges, R.S., Bialos, M., Hammer Jr., R.P. 2000. Expression of μ-opioid receptor mRNA in the medial preoptic area of juvenile rats. Developmental Brain Research.
  13. Mann, P.E., Foltz, G., Rigero, B.A., Bridges, R.S. 1999. The development of POMC gene expression in the medial basal hypothalamus of prepubertal rats. Developmental Brain Research.
  14. Bridges, R.S., Mann, P.E., Coppeta, J.S. 1999. Hypothalamic involvement in the regulation of maternal behaviour in the rat: Inhibitory roles for the ventromedial hypothalamus and the dorsal/anterior hypothalamic areas. Journal of Neuroendocrinology.
  15. Hopwood, R.M., Mann, P.E., Bridges, R.S. 1998. Reproductive experience and opioid regulation of luteinizing hormone release in female rats. Journal of Reproduction and Fertility.
  16. Mann, P.E., Rubin, B.S., Bridges, R.S. 1997. Differential proopiomelanocortin gene expression in the medial basal hypothalamus of rats during pregnancy and lactation. Molecular Brain Research.
  17. Bridges, R.S., Henriquez, B.M., Sturgis, J.D., Mann, P.E. 1997. Reproductive experience reduces haloperidol-lnduced prolactin secretion in female rats. Neuroendocrinology.
  18. Bridges, R.S., Robertson, M.C., Shiu, R.P.C., Sturgis, J.D., Henriquez, B.M., Mann, P.E. 1997. Central lactogenic regulation of maternal behavior in rats: Steroid dependence, hormone specificity, and behavioral potencies of rat prolactin and rat placental lactogen I. Endocrinology.
  19. Zaias, J., Okimoto, L., Trivedi, A., Mann, P.E., Bridges, R.S. 1996. Inhibitory effects of naltrexone on the induction of parental behavior in juvenile rats. Pharmacology Biochemistry and Behavior.
  20. Bridges, R.S., Robertson, M.C., Shiu, R.P.C., Friesen, H.G., Stuer, A.M., Mann, P.E. 1996. Endocrine Communication between Conceptus and Mother: Placental Lactogen Stimulation of Maternal Behavior. Neuroendocrinology.

General Research Interests

  • Stress and the microbiome during pregnancy and lactation
  • Neurobiology of maternal behavior in rats

Selected Research Projects

  • The Involvement of the VMH in Maternal Behavior in Rats.
  • Hormone Receptor Silencing in the Study of Maternal Behavior.
  • Evaluation of Environmental Enrichment and Pup Exposure on Maternal Behavior Sensitization Latencies in Virgin Female Rats.


D.V.M. Program:

  • Anatomy I (141)
  • Anatomy II (142)

Graduate Program, TCSVM:

  • Biostatistics MS LAM (553)

Coordinator, Research Path:

  • Cummings School’s Research Path is for DVM candidates with an interest in pursuing research as part of their veterinary curriculum. It complements the funded programs that encourage students to perform research during the summer months. Students who sign up for the Research Path will be mentored by the Research Path Team to ensure that their interest is rewarded.
  • Research projects include both on and off campus opportunities, including international experiences. Research can be done during the school year and/or during the summer. Students can choose research topics in basic sciences and clinical sciences, including a variety of species.
  • Throughout the school year, students involved in the Research Path will meet to discuss a variety of topics pertinent to their proposed summer research. They will learn Excel, Qualtrics, RefWorks, and other programs and will receive help in writing their research proposals.

Selective Director :

  • Teaching Veterinary Gross Anatomy
  • Hands-On Biostatistics


Research Interests by Area

Neuroscience and Reproductive Biology
  • Postpartum Stress and the Microbiome

    Recent findings in mice and rats indicate that the gut microbiota can affect stress and anxiety.  It is well established that the reproductive states of pregnancy and lactation are accompanied by reductions both in endocrine responsiveness to stress and reductions in anxiety.  The goal of this research is to identify those bacteria and bacterial metabolites that alter the neural circuits involved with stress and anxiety as a function of reproductive state. The goal of these studies would be the identification of potential therapies that could be used to reduce anxiety during the postpartum period. This project is a collaboration with members of the Department of Infectious Disease and Global Health. Learn more.

  • Neurobiology of Maternal Behavior

    Appropriate coordination of the reproductive axis is critical for species propagation. In mammals, reproductive processes and associated behaviors are regulated by the central nervous system. Neural signals are critical for synchronizing the release of hormones in response to developmental, experiential, and environmental factors. In addition, the brain controls the expression of behaviors necessary for mating and parenting. Dysregulation of the reproductive axis can have significant consequences for the individual, their offspring, and the species. Learn more.

Major Specialized Equipment

  • Cryostats
  • Microscopes
  • Behavioral Apparatus