Cummings School of Veterinary Medicine at Tufts University
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Assistant Professor

Campus Phone:
508-887-4756

Education

  • PhD - Albert Einstein College of Medicine - 1992 
  • MS - Albert Einstein College of Medicine - 1991
  • BA - Hamline University - 1989

Board Certification

  • Diplomate of the American College of Veterinary Microbiologists (DACVM)

A single VHH-based toxin-neutralizing agent and an effector antibody protect mice against challenge with Shiga toxins 1 and 2.

Author(s):Tremblay, J.M. | Mukherjee, J. | Leysath, C.E. | Debatis, M. | Ofori, K. | Baldwin, K. | Boucher, C. | Peters, R. | Beamer, G. | Sheoran, A. | Bedenice, D. | Tzipori, S. | Shoemaker, C.B.
Publication year: 2013
Journal / Book title: Infection and immunity

Antibody against TcdB, but not TcdA, prevents development of gastrointestinal and systemic clostridium difficile disease

Author(s):Steele, J. | Mukherjee, J. | Parry, N. | Tzipori, S.
Publication year: 2013
Journal / Book title: Journal of Infectious Diseases

Sheep monoclonal antibodies prevent systemic effects of botulinum neurotoxin A1

Author(s):Mukherjee, J. | McCann, C. | Ofori, K. | Hill, J. | Baldwin, K. | Shoemaker, C.B. | Harrison, P. | Tzipori, S.
Publication year: 2012
Journal / Book title: Toxins

Allele- and Tir-independent functions of intimin in diverse animal infection models

Author(s):Mallick, E.M. | Brady, M.J. | Luperchio, S.A. | Vanguri, V.K. | Magoun, L. | Liu, H. | Sheppard, B.J. | Mukherjee, J. | Donohue-Rolfe, A. | Tzipori, S. | Leong, J.M. | Schauer, D.B.
Publication year: 2012
Journal / Book title: Frontiers in Microbiology

Biodistribution and elimination kinetics of systemic Stx2 by the Stx2A and Stx2B subunit-specific human monoclonal antibodies in mice

Author(s):Sheoran, A. | Jeong, K.-I. | Mukherjee, J. | Wiffin, A. | Singh, P. | Tzipori, S.
Publication year: 2012
Journal / Book title: BMC Immunology

A novel strategy for development of recombinant antitoxin therapeutics tested in a mouse botulism model

Author(s):Mukherjee, J. | Tremblay, J.M. | Leysath, C.E. | Ofori, K. | Baldwin, K. | Feng, X. | Bedenice, D. | Webb, R.P. | Wright, P.M. | Smith, L.A. | Tzipori, S. | Shoemaker, C.B.
Publication year: 2012
Journal / Book title: PLoS ONE

Enhanced actin pedestal formation by enterohemorrhagic Escherichia coli O157:H7 adapted to the mammalian host

Author(s):Brady, M.J. | Radhakrishnan, P. | Liu, H. | Magoun, L. | Murphy, K.C. | Mukherjee, J. | Donohue-Rolfe, A. | Tzipori, S. | Leong, J.M.
Publication year: 2011
Journal / Book title: Frontiers in Microbiology

Efficient serum clearance of botulinum neurotoxin achieved using a pool of small antitoxin binding agents

Author(s):Sepulveda, J. | Mukherjee, J. | Tzipori, S. | Simpson, L.L. | Shoemaker, C.B.
Publication year: 2010
Journal / Book title: Infection and Immunity

Serum concentrations of the third component of complement in healthy dogs and dogs with protein-losing nephropathy

Author(s):Acierno, M.J. | Labato, M.A. | Stern, L.C. | Mukherjee, J. | Jakowski, R.M. | Ross, L.A.
Publication year: 2006
Journal / Book title: American Journal of Veterinary Research

Human antibody against Shiga toxin 2 administered to piglets after the onset of diarrhea due to Escherichia coli O157:H7 prevents fatal systemic complications

Author(s):Sheoran, A.S. | Chapman-Bonofiglio, S. | Harvey, B.R. | Mukherjee, J. | Georgiou, G. | Donohue-Rolfe, A. | Tzipori, S.
Publication year: 2005
Journal / Book title: Infection and Immunity

Production and characterization of protective human antibodies against Shiga toxin 1

Author(s):Mukherjee, J. | Chios, K. | Fishwild, D. | Hudson, D. | O'Donnell, S. | Rich, S.M. | Donohue-Rolfe, A. | Tzipori, S.
Publication year: 2002
Journal / Book title: Infection and Immunity

Antibody efficacy in murine pulmonary Cryptococcus neoformans infection: A role for nitric oxide

Author(s):Rivera, J. | Mukherjee, J. | Weiss, L.M. | Casadevall, A.
Publication year: 2002
Journal / Book title: Journal of Immunology

Human Stx2-specific monoclonal antibodies prevent systemic complications of Escherichia coli O157:H7 infection

Author(s):Mukherjee, J. | Chios, K. | Fishwild, D. | Hudson, D. | O'Donnell, S. | Rich, S.M. | Donohue-Rolfe, A. | Tzipori, S.
Publication year: 2002
Journal / Book title: Infection and Immunity

Urease as a virulence factor in experimental cryptococcosis

Author(s):Cox, G.M. | Mukherjee, J. | Cole, G.T. | Casadevall, A. | Perfect, J.R.
Publication year: 2000
Journal / Book title: Infection and Immunity

Molecular and idiotypic analyses of the antibody response to Cryptococcus neoformans glucuronoxylomannan-protein conjugate vaccine in autoimmune and nonautoimmune mice

Author(s):Nussbaum, G. | Anandasabapathy, S. | Mukherjee, J. | Fan, M. | Casadevall, A. | Scharff, M.D.
Publication year: 1999
Journal / Book title: Infection and Immunity

Antibody-based protection of gnotobiotic piglets infected with Escherichia coli O157:H7 against systemic complications associated with Shiga toxin 2

Author(s):Donohue-Rolfe, A. | Kondova, I. | Mukherjee, J. | Chios, K. | Hutto, D. | Tzipori, S.
Publication year: 1999
Journal / Book title: Infection and Immunity

Monoclonal antibodies reveal additional epitopes of serotype D Cryptococcus neoformans capsular glucuronoxylomannan that elicit protective antibodies

Author(s):Mukherjee, J. | Kozel, T.R. | Casadevaii, A.
Publication year: 1998
Journal / Book title: Journal of Immunology

Effect of immune mechanisms on the pharmacokinetics and organ distribution of Cryptococcal polysaccharide

Author(s):Lendvai, N. | Casadevall, A. | Liang, Z. | Goldman, D.L. | Mukherjee, J. | Zuckier, L.
Publication year: 1998
Journal / Book title: Journal of Infectious Diseases

Characterization of a murine monoclonal antibody to Cryptococcus neoformans polysaccharide that is a candidate for human therapeutic studies

Author(s):Casadevall, A. | Cleare, W. | Feldmesser, M. | Glatman-Freedman, A. | Goldman, D.L. | Kozel, T.R. | Lendvai, N. | Mukherjee, J. | Pirofski, L.-A. | Rivera, J. | Rosas, A.L. | Scharff, M.D. | Valadon, P. | Westin, K. | Zhong, Z.
Publication year: 1998
Journal / Book title: Antimicrobial Agents and Chemotherapy

Microevolution of a standard strain of Cryptococcus neoformans resulting in differences in virulence and other phenotypes

Author(s):Franzot, S.P. | Mukherjee, J. | Cherniak, R. | Chen, L.-C. | Hamdan, J.S. | Casadevall, A.
Publication year: 1998
Journal / Book title: Infection and Immunity

General Research Interests

Development of immune-based methods for diagnosis, therapy, and prevention of infectious and toxin-mediated diseases of human, veterinary and/or zoonotic concern; animal model development; in vivo evaluation of candidate therapeutics; veterinary microbiology and parasitology.

Research Interests by Area

Infectious Diseases: Prevention and Control
  • Botulism antidotes and anti-toxins

Laboratory Personnel

  • Karen Baldwin, Animal Specialist
  • Courtney Boucher, Research Technician
  • Kwasi Ofori, Research Assistant