Cummings School of Veterinary Medicine at Tufts University
Giovanni F. Widmer

Professor

Molecular Biology of Protozoan Parasites, Microbial Pathogenesis

Education

  • PhD - London School of Hygiene and Tropical Medicine - 1986

Population structure of natural and propagated isolates of Cryptosporidium parvum, C.hominis and C.meleagridis

Author(s):Widmer, G. | Ras, R. | Chalmers, R.M. | Elwin, K. | Desoky, E. | Badawy, A.
Publication year: 2014
Journal / Book title: Environmental Microbiology

A highly divergent 33 kDa cryptosporidium parvum antigen

Author(s):Jenkins, M.C. | Widmer, G. | O'Brien, C. | Bauchan, G. | Murphy, C. | Santin, M. | Fayer, R.
Publication year: 2014
Journal / Book title: Journal of Parasitology

Frequent occurrence of mixed enterocytozoon bieneusi infections in humans

Author(s):Widmer, G. | Dilo, J. | Tumwine, J.K. | Tzipori, S. | Akiyoshi, D.E.
Publication year: 2013
Journal / Book title: Applied and Environmental Microbiology

A pig model of the human gastrointestinal tract

Author(s):Zhang, Q. | Widmer, G. | Tzipori, S.
Publication year: 2013
Journal / Book title: Gut Microbes

Evidence that cryptosporidium parvum populations are panmictic and unstructured in the upper midwest of the united states

Author(s):Herges, G.R. | Widmer, G. | Clark, M.E. | Khan, E. | Giddings, C.W. | Brewer, M. | McEvoy, J.M.
Publication year: 2012
Journal / Book title: Applied and Environmental Microbiology

Survey and genetic characterization of wastewater in Tunisia for Cryptosporidium spp., Giardia duodenalis, Enterocytozoon bieneusi, Cyclospora cayetanensis and Eimeria spp.

Author(s):Ayed, L.B. | Yang, W. | Widmer, G. | Cama, V. | Ortega, Y. | Xiao, L.
Publication year: 2012
Journal / Book title: Journal of Water and Health

Comparative genome analysis of two Cryptosporidium parvum isolates with different host range

Author(s):Widmer, G. | Lee, Y. | Hunt, P. | Martinelli, A. | Tolkoff, M. | Bodi, K.
Publication year: 2012
Journal / Book title: Infection, Genetics and Evolution

Evidence of host-associated populations of Cryptosporidium parvum in Italy

Author(s):Drumo, R. | Widmer, G. | Morrison, L.J. | Tait, A. | Grelloni, V. | D'Avino, N. | Pozio, E. | Cacciò, S.M.
Publication year: 2012
Journal / Book title: Applied and Environmental Microbiology

Evidence of host-associated populations of Cryptosporidium parvum in Italy

Author(s):Drumo, R. | Widmer, G. | Morrison, L.J. | Tait, A. | Grelloni, V. | D'Avino, N. | Pozio, E. | Cacciò, S.M.
Publication year: 2012
Journal / Book title: Applied and Environmental Microbiology

Infection with Cryptosporidium hominis provides incomplete protection of the host against Cryptosporidium parvum

Author(s):Sheoran, A. | Wiffin, A. | Widmer, G. | Singh, P. | Tzipori, S.
Publication year: 2012
Journal / Book title: Journal of Infectious Diseases

Genomics and population biology of Cryptosporidium species

Author(s):Widmer, G. | Sullivan, S.
Publication year: 2012
Journal / Book title: Parasite Immunology

Cryptosporidium meleagridis: Infectivity in healthy adult volunteers

Author(s):Chappell, C.L. | Okhuysen, P.C. | Langer-Curry, R.C. | Akiyoshi, D.E. | Widmer, G. | Tzipori, S.
Publication year: 2011
Journal / Book title: American Journal of Tropical Medicine and Hygiene

A comparison of the Giardia lamblia trophozoite and cyst transcriptome using microarrays

Author(s):Faghiri, Z. | Widmer, G.
Publication year: 2011
Journal / Book title: BMC Microbiology

High-throughput screening in suboptimal growth conditions identifies agonists of Giardia lamblia proliferation

Author(s):Faghiri, Z. | Santiago, R.B. | Wu, Z. | Widmer, G.
Publication year: 2011
Journal / Book title: Parasitology

Comparison of single- and multilocus genetic diversity in the protozoan parasites cryptosporidium parvum and C. hominis

Author(s):Widmer, G. | Lee, Y.
Publication year: 2010
Journal / Book title: Applied and Environmental Microbiology

Cell sorting-assisted microarray profiling of host cell response to Cryptosporidium parvum infection

Author(s):Yang, Y.-L. | Buck, G.A. | Widmer, G.
Publication year: 2010
Journal / Book title: Infection and Immunity

Host-specific segregation of ribosomal nucleotide sequence diversity in the microsporidian Enterocytozoon bieneusi

Author(s):Widmer, G. | Akiyoshi, D.E.
Publication year: 2010
Journal / Book title: Infection, Genetics and Evolution

Meta-analysis of a polymorphic surface glycoprotein of the parasitic protozoa Cryptosporidium parvum and Cryptosporidium hominis

Author(s):Widmer, G.
Publication year: 2009
Journal / Book title: Epidemiology and Infection

Over-expression and localization of a host protein on the membrane of Cryptosporidium parvum infected epithelial cells

Author(s):Yang, Y.-L. | Serrano, M.G. | Sheoran, A.S. | Manque, P.A. | Buck, G.A. | Widmer, G.
Publication year: 2009
Journal / Book title: Molecular and Biochemical Parasitology

Cryptosporidium parvum DNA replication in cell-free culture

Author(s):Zhang, L. | Sheoran, A.S. | Widmer, G.
Publication year: 2009
Journal / Book title: Journal of Parasitology

General Research Interests

  • Molecular biology of protozoan parasites
  • Waterborne pathogens

Selected Research Projects

  • Genetics of Cryptosporidium parvum.
  • Cryptosporidium genome sequencing.
  • Detection and genotyping of Cryptospordium oocysts and Giardia cysts in water.
  • Analysis of complex microbial populations using high-throughput sequencing.

Research Interests by Area

Infectious Diseases: Prevention and Control
  • Detection in and removal of Cryptosporidium from water; molecular markers of Giardia lamblia cyst infectivity
Infectious Diseases: Genetics and Genomics
  • Comparative genomics of Cryptosporidium species