Cummings School of Veterinary Medicine at Tufts University
Elizabeth McCone Byrnes

Associate Professor

Neuroendocrinology
Section of Neuroscience and Reproductive Biology

Campus Phone:
508-839-7986

Fax:
508-839-7091

Education

  • BA - University of Massachusetts at Boston - 1991
  • PhD - The Ohio State University - 1995

Sex-and age-specific differences in relaxin family peptide receptor expression within the hippocampus and amygdala in rats

Author(s):Meadows, K.L. | Byrnes, E.M.
Publication year: 2015
Journal / Book title: Neuroscience

Housing environment modulates physiological and behavioral responses to anxiogenic stimuli in trait anxiety male rats

Author(s):Ravenelle, R. | Santolucito, H.B. | Byrnes, E.M. | Byrnes, J.J. | Donaldson, S.T.
Publication year: 2014
Journal / Book title: Neuroscience

The impact of exposure to addictive drugs on future generations: Physiological and behavioral effects

Author(s):Vassoler, F.M. | Byrnes, E.M. | Pierce, R.C.
Publication year: 2014
Journal / Book title: Neuropharmacology

Next generation effects of female adolescent morphine exposure: Sex-specific alterations in response to acute morphine emerge before puberty

Author(s):Vassoler, F.M. | Johnson-Collins, N.L. | Carini, L.M. | Byrnes, E.M.
Publication year: 2014
Journal / Book title: Behavioural Pharmacology

Reproductive Experience Alters Neural and Behavioural Responses to Acute Oestrogen Receptor α Activation

Author(s):Byrnes, E.M. | Casey, K. | Carini, L.M. | Bridges, R.S.
Publication year: 2013
Journal / Book title: Journal of Neuroendocrinology

Female adolescent exposure to cannabinoids causes transgenerational effects on morphine sensitization in female offspring in the absence of in utero exposure

Author(s):Vassoler, F.M. | Johnson, N.L. | Byrnes, E.M.
Publication year: 2013
Journal / Book title: Journal of Psychopharmacology

Environmental enrichment effects on the neurobehavioral profile of selective outbred trait anxiety rats

Author(s):Ravenelle, R. | Byrnes, E.M. | Byrnes, J.J. | McInnis, C. | Park, J.H. | Donaldson, S.T.
Publication year: 2013
Journal / Book title: Behavioural Brain Research

Multigenerational effects of adolescent morphine exposure on dopamine D2 receptor function

Author(s):Byrnes, J.J. | Johnson, N.L. | Carini, L.M. | Byrnes, E.M.
Publication year: 2013
Journal / Book title: Psychopharmacology

Cannabinoid exposure in adolescent female rats induces transgenerational effects on morphine conditioned place preference in male offspring

Author(s):Byrnes, J.J. | Johnson, N.L. | Schenk, M.E. | Byrnes, E.M.
Publication year: 2012
Journal / Book title: Journal of Psychopharmacology

Reproductive experience modifies the effects of estrogen receptor alpha activity on anxiety-like behavior and corticotropin releasing hormone mRNA expression

Author(s):Byrnes, E.M. | Casey, K. | Bridges, R.S.
Publication year: 2012
Journal / Book title: Hormones and Behavior

Adolescent opiate exposure in the female rat induces subtle alterations in maternal care and transgenerational effects on play behavior

Author(s):Johnson, N.L. | Carini, L. | Schenk, M.E. | Stewart, M. | Byrnes, E.M.
Publication year: 2011
Journal / Book title: Frontiers in Psychiatry

Accelerated maternal responding following intra-VTA pertussis toxin treatment

Author(s):Byrnes, J.J. | Gleason, E.D. | Schoen, M.T. | Lovelock, D.F. | Carini, L.M. | Byrnes, E.M. | Bridges, R.S.
Publication year: 2011
Journal / Book title: Behavioural Brain Research

Amphetamine sensitization in reproductively experienced female rats

Author(s):Byrnes, J.J. | Bridges, R.S. | Byrnes, E.M.
Publication year: 2011
Journal / Book title: Neuroscience Letters

Reproductive experience alters prolactin receptor expression in mammary and hepatic tissues in female rats

Author(s):Bridges, R.S. | Scanlan, V.F. | Lee, J.-O. | Byrnes, E.M.
Publication year: 2011
Journal / Book title: Biology of Reproduction

Adolescent opioid exposure in female rats: Transgenerational effects on morphine analgesia and anxiety-like behavior in adult offspring

Author(s):Byrnes, J.J. | Babb, J.A. | Scanlan, V.F. | Byrnes, E.M.
Publication year: 2011
Journal / Book title: Behavioural Brain Research

Vasopressin mediates enhanced offspring protection in multiparous rats

Author(s):Nephew, B.C. | Byrnes, E.M. | Bridges, R.S.
Publication year: 2010
Journal / Book title: Neuropharmacology

Enhanced Maternal Aggression and Associated Changes in Neuropeptide Gene Expression in Multiparous Rats

Author(s):Nephew, B.C. | Bridges, R.S. | Lovelock, D.F. | Byrnes, E.M.
Publication year: 2009
Journal / Book title: Behavioral Neuroscience

Differential expression of oestrogen receptor α following reproductive experience in young and middle-aged female rats

Author(s):Byrnes, E.M. | Babb, J.A. | Bridges, R.S.
Publication year: 2009
Journal / Book title: Journal of Neuroendocrinology

Neuroendocrine and Behavioral Adaptations Following Reproductive Experience in the Female Rat

Author(s):Byrnes, E.M. | Nephew, B.C. | Bridges, R.S.
Publication year: 2008
Journal / Book title: Neurobiology of the Parental Brain

Chronic morphine exposure during puberty induces long-lasting changes in opioid-related mRNA expression in the mediobasal hypothalamus

Author(s):Byrnes, E.M.
Publication year: 2008
Journal / Book title: Brain Research

General Research Interests

  • Neuroendrocrinology
  • Maternal behavior
  • Animal models of drug abuse

Selected Research Projects

  • How Motherhood Changes the Brain - This project examines the long term changes in the brain following pregnancy. One of the primary focus areas is the formation of memories that increase the female's motivation to behave maternally toward foster young. Specific alterations in the brain in conjunction with behavioral changes are explored.
  • Neural and Endocrine Consquences of Parity - This project examines the underlying mechanisms which contribute to alterations in the endocrine system following pregnancy and lactation. The primary focus areas are hypothalamic regulation of prolactin secretion and long term changes in estrogen receptor expression in the brain.
  • Reproductive Consquences of Pubertal Opiate Abuse - This project examines the effect of opiate abuse during puberty on future maternal behavior, including lactation. In addition, this project also explores how a history of drug abuse in the mother can alter the propensity of her offspring to abuse drugs.

Research Interests by Area

Reproductive Biology and Neuroscience
  • Endocrine regulation of maternal behavior in rats

Laboratory Personnel

  • Fair Vassoler, Post-Doctoral Scholar
  • Kristy Meadows, MS Student, Comparative Biomedical Sciences