Cummings School of Veterinary Medicine at Tufts University
Christopher M. Schonhoff

Research Assistant Professor

Signaling by Nitric Oxide

Campus Phone:


  • PhD - UMASS Medical School - 2000
  • BS - Boston College - 1992
  1. Park, S. W., Schonhoff, C. M., Webster, C. R., and Anwer, M. S. (2012) Protein kinase Cdelta differentially regulates cAMP-dependent translocation of NTCP and MRP2 to the plasma membrane, Am J Physiol Gastrointest Liver Physiol 303, G657-665.
  2. Schonhoff, C. M., and Benhar, M. (2011) Analysis of protein S-nitrosylation, Curr Protoc Protein Sci Chapter 14, Unit14 16.
  3. Schonhoff, C. M., Ramasamy, U., and Anwer, M. S. (2011) Nitric oxide-mediated inhibition of taurocholate uptake involves S-nitrosylation of NTCP, Am J Physiol Gastrointest Liver Physiol 300, G364-370.
  4. Schonhoff, C. M., Webster, C. R., and Anwer, M. S. (2010) Cyclic AMP stimulates Mrp2 translocation by activating p38{alpha} MAPK in hepatic cells, Am J Physiol Gastrointest Liver Physiol 298, G667-674.
  5. Schonhoff, C. M., Yamazaki, A., Hohenester, S., Webster, C. R., Bouscarel, B., and Anwer, M. S. (2009) PKC{epsilon}-dependent and -independent effects of taurolithocholate on PI3K/PKB pathway and taurocholate uptake in HuH-NTCP cell line, Am J Physiol Gastrointest Liver Physiol 297, G1259-1267.
  6. Godoy, L. C., Munoz-Pinedo, C., Castro, L., Cardaci, S., Schonhoff, C. M., King, M., Tortora, V., Marin, M., Miao, Q., Jiang, J. F., Kapralov, A., Jemmerson, R., Silkstone, G. G., Patel, J. N., Evans, J. E., Wilson, M. T., Green, D. R., Kagan, V. E., Radi, R., and Mannick, J. B. (2009) Disruption of the M80-Fe ligation stimulates the translocation of cytochrome c to the cytoplasm and nucleus in nonapoptotic cells, Proc. Natl. Acad. Sci. U. S. A.106, 2653-2658.
  7. Schonhoff, C. M., Thankey, K., Webster, C. R., Wakabayashi, Y., Wolkoff, A. W., and Anwer, M. S. (2008) Rab4 facilitates cyclic adenosine monophosphate-stimulated bile acid uptake and Na+-taurocholate cotransporting polypeptide translocation, Hepatology 48, 1665-1670.
  8. Mannick, J. B., and Schonhoff, C. M. (2008) Measurement of protein S-nitrosylation during cell signaling, Methods Enzymol. 440, 231-242.
  9. Schonhoff, C. M., Gillin, H., Webster, C. R., and Anwer, M. S. (2008) Protein kinase Cdelta mediates cyclic adenosine monophosphate-stimulated translocation of sodium taurocholate cotransporting polypeptide and multidrug resistant associated protein 2 in rat hepatocytes,Hepatology 47, 1309-1316.
  10. Schonhoff, C. M., Matsuoka, M., Tummala, H., Johnson, M. A., Estevez, A. G., Wu, R., Kamaid, A., Ricart, K. C., Hashimoto, Y., Gaston, B., Macdonald, T. L., Xu, Z., and Mannick, J. B. (2006) S-nitrosothiol depletion in amyotrophic lateral sclerosis, Proc. Natl. Acad. Sci. U. S. A. 103, 2404-2409.

General Research Interests

  • Signaling by nitric oxide, liver physiology and livery pathophysiology