Sarah K. Crain - MS, DACVIM (SAIM), PhD Candidate

Dr. Sarah Crain is an internist at the Foster Hospital for Small Animals at the Cummings School of Veterinary Medicine at Tufts University. She commonly treats acute and chronic kidney disease, inflammatory bowel disease, and endocrine diseases including diabetes and Cushing’s disease. She has a particular interest in intestinal and pancreatic disease, immune diseases, kidney diseases, dialysis, endoscopic procedures and addressing pain management in older patients. Additionally, Dr. Crain is currently pursuing a PhD in regenerative medicine at Cummings School.

Dr. Crain grew up in Northern New Jersey where she had an early interest in veterinary medicine. She received her doctorate in veterinary medicine from the University of Minnesota, where she also completed an internal medicine residency.  Later, she completed a residency at North Carolina State University.

When she is not at work, Dr. Crain enjoys reading, cooking, traveling, painting, drawing, and spending time with her tuxedo cat, Lando, and her beagle, Baxter.


  • MS – University of Minnesota, 2014
  • DVM – University of Minnesota, 2008
  • BA – Oberlin College, 2002

Board Certification

  • Crain SK, Sharkey LC, Cordner AP, Knudson C, Armstrong PJ. Safety of ultrasound-guided fine needle aspirates of the feline pancreas: A case-control study. J Feline Med Surg. Nov 2014
  • Rojas-Temahuay G, Crain S, Benson C, Sharkey L, Nothnagel G. Cold Agglutinin Acticvity in 2 Dogs. Vet Clin Pathol. Sept 2014
  • Garvin MC, Marra PP, Crain SK. Prevalence of hematozoa in overwintering American redstarts (Setophaga ruticilla): no evidence for local transmission. J Wildl Dis. Jan 2004
  • Swerdlow NR, Shoemaker JM, Platten A, Pitcher L, Goins J, Crain S. Heritable differences in the effects of amphetamine but not DOI on startle gating in albino and hooded outbred rat strains. Pharmacol Biochem Behav. April 2003

General Research Interests

  • Stem cells and extracellular vesicles
  • Canine immunology

Selected Research Projects

  • Evaluation of mechanisms of stem cell immunosuppression in canine white blood cells
  • Evaluation of the mechanisms stem cell-derived extracellular vesicles in canine immune regulation 

Research and Clinical Interests

  • Stem cell mechanisms of immunosuppression
  • Extracellular vesicles and immune regulation
  • Canine and feline immunology and hematology
  • Canine and feline gastroenterology and inflammatory bowel diseases
  • Canine and feline pancreatic disease


  • Problem Based Learning
  • Clinical Skills
  • Physiology

Major Specialized Equipment

  • Cell culture
  • Nanoparticle Tracking Analysis
  • Ultracentrifugation
  • Confocal microscopy