John E. Rush - DVM, MS, DACVECC, DACVIM

John E. Rush
Nutritional Management of Cardiovascular Disease, Cardiology, Critical Care
Cardiology

As a veterinary cardiologist,†Dr.†John Rush has a special interest in drug and dietary therapies for the treatment of heart disease in small animals. He also performs many catheter-based procedures (interventional radiology), including the placement of pacemakers, coils and stents. In addition to his clinical duties,†Dr.†Rush teaches cardiology to second and third-year students and mentors fourth-year students in the Foster Hospital for Small Animals.

Growing up near Cleveland,†Dr.†Rush had a natural affinity for science and spent a great deal of time at the Lake Erie Nature and Science Center.†I collected insects, and if I had not become a veterinarian I might have been an entomologist,†he says. He attended The Ohio State University for his undergraduate and veterinary degrees, then furthered his training in New York and Wisconsin. Drawn to the Cummings School of Veterinary Medicine by a love of teaching, he joined the faculty here more than 20 years ago.

He likes the mix of teaching, clinical research, and caring for dogs and cats with heart disease, as well as the motivated and gifted students of the Cummings School. He has served as the primary mentor for two dozen veterinary residents in emergency and critical care and cardiology and has published on topics ranging from heart failure and respiratory distress to quality-of-life issues for pets.

Off-campus,†Dr.†Rush is very involved with both the American College of Veterinary Internal Medicine and the American College of Emergency and Critical Care, and he is a diplomate of both societies. He has three dogs and counts home improvement as his favorite pastime.

Education

  • DVM - Ohio State University - 1984
  • MS - Ohio State University - 1984

Board Certification

  • Cardiology (ACVIM)
  • Emergency and Critical Care (ACVECC)

Differentiation of Cardiac from Noncardiac Pleural Effusions in Cats using Second-Generation Quantitative and Point-of-Care NT-proBNP Measurements

Author(s):Hezzell, M.J. | Rush, J.E. | Humm, K. | Rozanski, E.A. | Sargent, J. | Connolly, D.J. | Boswood, A. | Oyama, M.A.
Publication year: 2016
Journal / Book title: Journal of Veterinary Internal Medicine

The use of rivaroxaban for the treatment of thrombotic complications in four dogs

Author(s):Yang, V.K. | Cunningham, S.M. | Rush, J.E. | de Laforcade, A.
Publication year: 2016
Journal / Book title: Journal of Veterinary Emergency and Critical Care

Assessment of the responsiveness of the Cats' Assessment Tool for Cardiac Health (CATCH) Questionnaire

Author(s):Rush, J.E. | Roderick, K.V. | Freeman, L.M. | Cunningham, S.M. | Yang, V.K. | Bulmer, B.J. | Antoon, K.N.
Publication year: 2015
Journal / Book title: Journal of Veterinary Cardiology

Pilot study of a myostatin antagonist in dogs with cardiac cachexia

Author(s):Freeman, L.M. | Rush, J.E. | Cunningham, S.M. | Yang, V.K. | Bulmer, B.J.
Publication year: 2015
Journal / Book title: Journal of Veterinary Cardiology

Expression profiling of circulating microRNAs in canine myxomatous mitral valve disease

Author(s):Li, Q. | Freeman, L.M. | Rush, J.E. | Laflamme, D.P.
Publication year: 2015
Journal / Book title: International Journal of Molecular Sciences

Pulmonary artery dissection in eight dogs with patent ductus arteriosus

Author(s):Scansen, B.A. | Simpson, E.M. | López-Alvarez, J. | Thomas, W.P. | Bright, J.M. | Eason, B.D. | Rush, J.E. | Dukes-Mcewan, J. | Green, H.W. | Cunningham, S.M. | Visser, L.C. | Kent, A.M. | Schober, K.E.
Publication year: 2015
Journal / Book title: Journal of Veterinary Cardiology

Congenital cardiac malformation with three-chambered right atrium and a persistent left cranial vena cava in a dog

Author(s):Yang, V.K. | Nussbaum, L. | Rush, J.E. | Cunningham, S.M. | Macgregor, J. | Antoon, K.N.
Publication year: 2015
Journal / Book title: Journal of Veterinary Cardiology

Relationship of body size to metabolic markers and left ventricular hypertrophy in cats

Author(s):Freeman, L.M. | Rush, J.E. | Feugier, A. | van Hoek, I.
Publication year: 2015
Journal / Book title: Journal of Veterinary Internal Medicine

Veterinary Medicine and Multi-Omics Research for Future Nutrition Targets: Metabolomics and Transcriptomics of the Common Degenerative Mitral Valve Disease in Dogs

Author(s):Li, Q. | Freeman, L.M. | Rush, J.E. | Huggins, G.S. | Kennedy, A.D. | Labuda, J.A. | Laflamme, D.P. | Hannah, S.S.
Publication year: 2015
Journal / Book title: OMICS A Journal of Integrative Biology

Relationship of plasma N-terminal pro-brain natriuretic peptide concentrations to heart failure classification and cause of respiratory distress in dogs using a 2nd generation ELISA assay

Author(s):Fox, P.R. | Oyama, M.A. | Hezzell, M.J. | Rush, J.E. | Nguyenba, T.P. | Defrancesco, T.C. | Lehmkuhl, L.B. | Kellihan, H.B. | Bulmer, B. | Gordon, S.G. | Cunningham, S.M. | Macgregor, J. | Stepien, R.L. | Lefbom, B. | Adin, D. | Lamb, K.
Publication year: 2015
Journal / Book title: Journal of Veterinary Internal Medicine

Comparison of serum fatty acid concentrations in cats with hypertrophic cardiomyopathy and healthy controls

Author(s):Hall, D.J. | Freeman, L.M. | Rush, J.E. | Cunningham, S.M.
Publication year: 2014
Journal / Book title: Journal of Feline Medicine and Surgery

A randomized study assessing the effect of diet in cats with hypertrophic cardiomyopathy

Author(s):Freeman, L.M. | Rush, J.E. | Cunningham, S.M. | Bulmer, B.J.
Publication year: 2014
Journal / Book title: Journal of Veterinary Internal Medicine

ECG of the month

Author(s):Carvalho, K.N. | Rush, J.E. | Wetmore, L.A.
Publication year: 2014
Journal / Book title: Journal of the American Veterinary Medical Association

Multi-centered investigation of a point-of-care NT-proBNP ELISA assay to detect moderate to severe occult (pre-clinical) feline heart disease in cats referred for cardiac evaluation

Author(s):Machen, M.C. | Oyama, M.A. | Gordon, S.G. | Rush, J.E. | Achen, S.E. | Stepien, R.L. | Fox, P.R. | Saunders, A.B. | Cunningham, S.M. | Lee, P.M. | Kellihan, H.B.
Publication year: 2014
Journal / Book title: Journal of Veterinary Cardiology

Acquired gerbode defect and third-degree atrioventricular block secondary to vehicular trauma in a dog

Author(s):Cunningham, S.M. | Lindsey, K.J. | Rush, J.E.
Publication year: 2013
Journal / Book title: Journal of Veterinary Emergency and Critical Care

Nutritional Management of Cardiovascular Diseases

Author(s):Freeman, L.M. | Rush, J.E.
Publication year: 2013
Journal / Book title: Applied Veterinary Clinical Nutrition

Short-Term Effects of Atorvastatin in Normal Dogs and Dogs with Congestive Heart Failure Due to Myxomatous Mitral Valve Disease

Author(s):Cunningham, S.M. | Rush, J.E. | Freeman, L.M.
Publication year: 2013
Journal / Book title: Journal of Veterinary Internal Medicine

Clinical usefulness of an assay for measurement of circulating n-terminal pro-b-type natriuretic peptide concentration in dogs and cats with heart disease

Author(s):Oyama, M.A. | Boswood, A. | Connolly, D.J. | Ettinger, S.J. | Fox, P.R. | Gordon, S.G. | Rush, J.E. | Sisson, D.D. | Stepien, R.L. | Wess, G. | Zannad, F.
Publication year: 2013
Journal / Book title: Journal of the American Veterinary Medical Association

Evaluation of a training course in focused echocardiography for noncardiology house officers

Author(s):Tse, Y.C. | Rush, J.E. | Cunningham, S.M. | Bulmer, B.J. | Freeman, L.M. | Rozanski, E.A.
Publication year: 2013
Journal / Book title: Journal of Veterinary Emergency and Critical Care

Body size and metabolic differences in Maine Coon cats with and without hypertrophic cardiomyopathy

Author(s):Freeman, L.M. | Rush, J.E. | Meurs, K.M. | Bulmer, B.J. | Cunningham, S.M.
Publication year: 2013
Journal / Book title: Journal of Feline Medicine and Surgery

General Research Interests

  • Cardiovascular drug development for dogs and cats
  • ECG interpretation
  • Nutritional management of congestive heart failure
  • Veterinary critical care monitoring

Research Interests by Area

Spontaneous Animal Disease Models
  • Hyertrophic cardiomyopathy in cats, arrhythmogenic right ventricular cardiomyopathy in Boxer dogs, dilated cardiomyopathy in dogs, degenerative mitral valve disease in small dogs.

Research Interests by Organ System and Disease

Cardiovascular Diseases and Nutrition
  • Etiology of canine acquired valvular diseases and surgical interventions; genetic testing in cats with hypertrophic cardiomyopathy; Quality or quantity of life in dogs with cardiovascular disease
  • Tissue plasminogen activator in cats with ATE; NT-BNP in dogs with DCM, CVD and shortness of breath
  • Interventional radiography, genetic and nutritional factors for heart valve disease in dogs and cats, congestive heart failure, thromboelastography
  • Morphometrics in cats with hypertrophic cardiomyopathy
Nutritional Basis of Diseases
  • Nutritional management of congestive heart failure, new drugs for cardiovascular medicine, cardiac biomarkers.

Major Specialized Equipment

  • Echocardiography
  • Cardiac catheterization laboratory