Cummings School of Veterinary Medicine at Tufts University
Elizabeth McNiel

Oncology

Affiliations

Specialties

Education

  • PhD (Radiation Biology) - Colorado State University - 2000
  • DVM - Texas A&M University - 1992
  • BS - University of Texas - Austin - 1988

Board Certification

  • ACVIM - Oncology
  • ACVR - Radiation Oncology
  1. Rancillio N, Higuchi, T, Gagnon, J, McNiel, EA. Use of conformal radiation therapy for the treatment of a heart base chemodectoma in a dog. J Am Vet Med Assoc in press 2012.
  2. Erfourth TM, Scott MA, Wilson DV, McNiel EA. Erythrogram and biochemical changes following repeated propofol anesthesia in tumor-bearing dogs undergoing definitive radiation therapy. J Am Vet Med Assoc in press 2012.
  3. Sacornrattana O, Dervisis NG and McNiel EA. Abdominal ultrasonographic findings at diagnosis of osteosarcoma in dogs and association with treatment outcome. Veterinary and Comparative Oncology Vet Comp Oncol. 2012 Feb 2. [Epub ahead of print].
  4. Vail DM, von Euler H, Rusk A, Barber LG, Clifford CA, Elmslie RE, Fulton L, Hirschberger J, Klein M, London C, Martano M, McNiel EA, Morris JS, Northrup NC, Phillips B, Polton G, Post GS, Rosenberg MP, Ruslander D, Sahora AI, Siegel S, Thamm DH, Westberg S, Winter J, Khanna C. A randomized trial investigating the efficacy and safety of water soluble micellar paclitaxel (PaccalŽ Vet) for treatment of nonresectable grade 2 or 3 mast cell tumors in dogs. Journal of Veterinary Internal Medicine J Vet Intern Med. 2012 Mar 6. [Epub ahead of print].
  5. Husbands, B.D., McNiel, E.A., Modiano J.F. Initial Evaluation of Safety of Wide Field Radiation in the treatment of Hematopoietic Neoplasia in the Cat. Vet Radiol Ultrasound 51(6):688-696, 2010.
  6. Sotirakopoulos, A.J., Armstrong, P.J., Heath, L., Madrill, N.J., McNiel, E.A. Evaluation of microsatellite instability in urine for the diagnosis of transitional cell carcinoma of the lower urinary tract in dogs. J Vet Int Med. 24(6):1445-1451, 2010.
  7. Harrison, T.M., Dominguez, P., Hanzlik, K., Sikarskie, J.G., Agnew, D., Bergin, I., Fitzgerald, S.D., Kitchell, B.E., McNiel, E.A. Treatment of an amelanotic melanoma using radiation therapy in a lesser madagascar hedgehog tenrec (echinops telfairi). J Zoo Wildlife Med4(1):152-157, 2010.
  8. Nadella, M.V.P., Kisseberth, W.C., Nadella, K.S., Thudi, N.K., Thamm, D.H., McNiel, E.A., Yilmaz, A. Boris-Lawrie, J. Rosol T.K. NOD/SCID mouse model of canine T-cell lymphoma with humoral hypercalcaemia of malignancy: Cytokine gene expression profiling and in vivo bioluminescent imaging. 6(1):39-54, 2008.

General Research Interests

Cancers occurring in pet animals are common and share morphology, biologic behavior and many molecular features with human cancers. Therefore cancers in pet animals provide a potentially useful means to understand cancers in all species. My roles as a both veterinary clinician and scientist facilitate the combination of molecular and cellular biologic techniques with veterinary clinical investigations. The overarching goals of this research are 1) to improve the ability to prevent, detect, and treat cancer and 2) to develop new animal models for translational cancer research. 

Selected Research Projects

  • Effects of anti-angiogenic therapy in feline oral squamous cell carcinoma.
  • Investigating canine hereditary Gastric carcinoma susceptibility.
  • DNA Mismatch repair in the biology of  bladder cancer.
  • Role of aluminum in feline vaccine-associated carcinogenesis.

Research Interests by Area

Spontaneous Animal Disease Models
  • Lymphoma, osteosarcoma, transitional cell carcinoma, prostatic cancer, hemangiosarcoma, mammary (breast) cancer, squamous cell carcinoma in cats

Research Interests by Organ System and Disease

Oncology and Cancer Research and Clinical Trials
  • Companion animals in translational cancer research, Chromatin Modification in Canine Cancer. Biological mechanisms of cancer; spontaneous animal disease models; radiation oncology.