Cummings School of Veterinary Medicine at Tufts University
Claire R. Sharp

Canine and Feline Sepsis

Emergency & Critical Care

Claire Sharp joined the Tufts Faculty in August of 2009, joining the faculty of one of the nation's busiest teaching Emergency and Critical Care services for pets. She has particular interests in trauma, systemic infections and respiratory failure requiring mechanical ventilation, and is board-certified by the American College of Veterinary Emergency and Critical Care.

Dr. Sharp grew up in Western Australia on a tiny tropical island in the Indian Ocean—the West Island in the atoll of the Cocos Keeling Islands. For as long as she could remember, she wanted to be a veterinarian. I can't remember a conscious decision to pursue this career, she says. It's just in my blood. After attending Perth, Australia's Murdoch University to earn both a bachelor's and a BVMS—the equivalent of a DVM degree in the United States—Dr. Sharp attended the University of Missouri to obtain a master's degree in veterinary clinical science and undertake a residency. While there, she earned awards for outstanding clinical service and her contribution to student teaching, which were awarded by the faculty and senior students respectively.

Dr. Sharp lives near the Cummings School campus with her cats, Margi and Minson. She enjoys traveling and hopes to resume competitive rowing soon.

Education

  • Masters of Science (Veterinary Clinical Sciences) - University of Missouri - 2010
  • Bachelor of Veterinary Medicine and Surgery - Murdoch University - 2002
  • Bachelor of Science (Veterinary Biology) - Murdoch University - 2000

Board Certification

  • Diplomate, American College of Veterinary Emergency & Critical Care (DACVECC)
  1. Sumner C, Rozanski EA, Sharp CR, Shaw SP. The use of deep oral swabs for bacterial culture as a surrogate for transoral tracheal wash cultures in dogs with pneumonia. J Vet Emerg Crit Care. In Press.
  2. Rutter CR, Rozanski EA, Sharp CR, Powell LL, Kent M. Ventilatory failure, ventilator management, and outcome in dogs with lower motor neuron disease; 15 cases (2003-2009). J Vet Emerg Crit Care. In Press.
  3. Donnelly K, DeClue AE, Sharp CR. What is your diagnosis? Suspected aldosterone secreting tumor in a 12-year-old labrador retriever. J Am Vet Med Assoc. 2010. In Press.
  4. DeClue AE, Osterbur K, Bigio A, Sharp CR. Evaluation of serum NT-pCNP as a diagnostic and prognostic biomarker for sepsis in dogs. J Vet Intern Med. 2011 May-Jun; 25(3):453-9.
  5. Buckley GJ, DeCubellis J, Sharp CR, Rozanski, EA. Cardiopulmonary cerebral resuscitation in hospitalized rabbits: 15 cases. J Exotic Pet Med. 2011; 20(1):46-50.
  6. DeClue AE, Delgado C, Chang C, Sharp CR. Clinical and immunologic assessment of sepsis and the systemic inflammatory response syndrome in cats. J Am Vet Med Assoc. 2011. Apr 1; 238(7):890-7.
  7. DeClue AE, Sharp CR, Cohen RL, Leverenz EF and Reinero CR. Cysteinyl-leukotriene receptor antagonism blunts the acute hypotensive response to endotoxin in cats. J Feline Med Surg (2010); 12, 754-759.
  8. Sharp CR, Ringen D and Nagy DW. Successful management of severe hypoventilation and hypercapnea in an alpaca (Vicugna pacos) with short-term mechanical ventilation. J Vet Emerg Crit Care (San Antonio). 2010; 20(2):258-263.
  9. Anastasio JA and Sharp CR. Acute aldicarb toxicosis in 15 dogs (2001-2009). J Vet Emerg Crit Care (San Antonio). 2011 Jun; 21(3):253-60.
  10. Sharp CR, DeClue AE, Haak C, Honaker A, Reinero CR. Evaluation of the antiendotoxin effects of polymyxin B in a feline model of endotoxemia. J Feline Med Surg. 2010 Apr; 12(4):278-85
  11. Sharp CR, Mann FA and Kerl ME. A comparison of total calcium, corrected calcium and ionized calcium concentrations as indicators of calcium homeostasis among hypoalbuminemic dogs requiring intensive care. J Vet Emerg Crit Care (San Antonio). 2009 Dec; 19(6):571-8.
  12. DeClue AE, Williams KJ, Sharp C, Haak C, Lechner E, Reinero CR. Systemic response to low-dose endotoxin infusion in cats. Vet Immunol Immunopathol. 2009 Dec 15; 132(2-4):167-74.

General Research Interests

  • Canine and Feline SIRS and Sepsis
  • Respiratory Diseases
  • Acute Respiratory Distress Syndrome (ARDS)
  • Polytrauma
  • Biomarkers for Cancer and Inflammatory Disease

Teaching

  • PBL I, II & III - Course Director
  • Immunology: Clinical Immunology, Congenital and Acquired Immunodeficiency Disorders
  • Small Animal Medicine - Selected Infectious Diseases, Coagulation Disorder
  • Cardiology - Shock
  • Toxicology - Plant Toxins, Renal Toxins

Research Interests by Area

Spontaneous Animal Disease Models
  • Sepsis in dogs and cats

Research Interests by Organ System and Disease

Emergency and Critical Care
  • Canine and feline sepsis, acute respiratory distress syndrome (ARDS), polytrauma. Sepsis, endotoxemia, and inflammatory biomarkers (dog and cat models), clinical critical care research

Visiting Professor

  • University of the West Indies - St. Augustine, Trinidad: Principles of Medicine & Small Animal Medicine