Dr. Gradil, LMV, was drawn to the field of veterinary medicine from an early age, having grown up in Africa as the son of a large animal veterinarian involved with the preservation of wildlife—namely large mammals such as elephants and rhinos. He is the reproductive consultant, or theriogenologist, for the Cummings School of Veterinary Medicine's Hospital for Large Animals. He also teaches equine reproduction in the fall for juniors as well as large animal rotations in reproduction.
In addition to being part of the faculty at the Cummings School, Dr.Gradil is also an associate professor at the University of Massachusetts Department of Veterinary and Animal Sciences. When asked what drew him to Tufts, he says,
Easy answer—the greatest group of people that I have worked with.
Dr. Gradil's areas of clinical expertise and interests are comparative reproduction in large and small animals and wildlife. His area of research expertise include determination of PLC zeta concentration in the sperm of dogs and horses and how it relates to fertility. He finds satisfaction in his fieldwork because it creates the opportunity to produce desirable offspring, relieve infertility and resolve difficult parturition. In terms of his biggest accomplishment at Cummings,Dr. Gradil says he is proudest of building a reputable referral service in reproduction for clients and colleagues in New England.
Dr. Gradil's honors include awards from US-AID, NATO, and the Veterinary Honor Society. He has also been a Fulbright fellow and a Rockefeller Fellow.
In his spare time, he enjoys hiking, pleasure riding, biking and kayaking. He currently resides in Amherst, Massachusetts.
- PhD in Theriogenology - University of Minnesota - 1987
- MSc in Theriogenology - University of Minnesota - 1982
- LMV - University of Lisbon, Portugal - 1977
- Diplomate of the American College of Theriogenology - 1998
- Gradil, C.M., Uricchio, C.K., Schwarz, A. 2019. Self-Assembling Intrauterine Device (Upod) Modulation of the Reproductive Cycle in Mares. Journal of Equine Veterinary Science.
- Frank, N., Hermida, P., Sanchez-Londoño, A., Singh, R., Gradil, C.M., Uricchio, C.K. 2017. Blood Glucose and Insulin Concentrations after Octreotide Administration in Horses With Insulin Dysregulation. Journal of Veterinary Internal Medicine.
- Pirie, C.G., Alario, A.F., Barysauskas, C.M., Gradil, C., Uricchio, C.K. 2014. Manual corneal thickness measurements of healthy equine eyes using a portable spectral-domain optical coherence tomography device. Equine Veterinary Journal.
- Gradil, C., McCarthy, R. 2013. Cryptorchidism. Small Animal Soft Tissue Surgery.
- O'Connor, C.L., Schweizer, C., Gradil, C., Schlafer, D., Lopate, C., Prociuk, U., Meyers-Wallen, V.N., Casal, M.L. 2011. Trisomy-X with estrous cycle anomalies in two female dogs. Theriogenology.
- Coyne, M.J., Cousin, H., Loftus, J.P., Johnson, P.J., Belknap, J.K., Gradil, C.M., Black, S.J., Alfandari, D. 2009. Cloning and expression of ADAM-related metalloproteases in equine laminitis. Veterinary Immunology and Immunopathology.
- Frederico, L.M., Gerard, M.P., Pinto, C.R.F., Gradil, C.M. 2007. Bilateral occurrence of granulosa-theca cell tumors in an Arabian mare. Canadian Veterinary Journal.
- Volkmann, D.H., Gilbert, R.O., Gradil, C., Linke, R. 2002. Leukocytes trapped in the fetal membranes of newborn foals. Theriogenology.
- Gradil, C.M., Ball, B.A. 2000. The use of pentoxifylline to improve motility of cryopreserved equine spermatozoa. Theriogenology.
- Gradil, C.M., Watson, R.E., Renshaw, R.W., Gilbert, R.O., Dubovi, E.J. 1999. Detection of bovine immunodeficiency virus DNA in the blood and semen of experimentally infected bulls. Veterinary Microbiology.
- Gradil, C., Dubuc, C., Eaglesome, M.D. 1996. Porcine reproductive and respiratory syndrome virus: Seminal transmission. Veterinary Record.
- Harding, M.J., Prud'homme, I., Gradil, C.M., Heckert, R.A., Riva, J., McLaurin, R., Dulac, G.C., Vydelingum, S. 1996. Evaluation of nucleic acid amplification methods for the detection of hog cholera virus. Journal of Veterinary Diagnostic Investigation.
- Gradil, C., Eaglesome, M.D., Stewart, B., Garcia, M.M., Quimby, F. 1995. Bactericidal effects of ozone at nonspermicidal concentrations.. Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire.
- Gradil, C.M., Harding, M.J., Lewis, K. 1994. Use of polymerase chain reaction to detect porcine parvovirus associated with swine embryos.. American journal of veterinary research.
- Gradil, C., Sampath, M., Eaglesome, M.D. 1994. Detection of verotoxigenic Escherichia coli in bull semen using the polymerase chain reaction. Veterinary Microbiology.
- Bielanski, A., Sampath, M., Gradil, C., Eaglesome, M.D., Garcia, M. 1994. In vitro Fertilization of Bovine Ova in the Presence of Campylobacter fetus subsp. venerealis. Reproduction in Domestic Animals.
- Gradil, C., Molitor, T., Harding, M., Crabo, B. 1990. Excretion of porcine parvovirus through the genital tract of boars.. American journal of veterinary research.
- Gradil, C.M., Joo, H.S., Molitor, T.W. 1990. Persistence of Porcine Parvovirus in Swine Infected In Utero and Followed through Maturity. Journal of Veterinary Medicine, Series B.
- Bane, D.P., James, J.E., Gradil, C.M., Molitor, T.W. 1990. In vitro exposure of preimplantation porcine embryos to porcine parvovirus. Theriogenology.
- Gradil, C., Joo, H.S. 1988. A radial immunodiffusion enzyme assay for detection of antibody to equine rhinopneumonitis virus (EHV-1) in horse serum. Veterinary Microbiology.
Research and Clinical Interests
- Breeding management, artificial insemination with fresh, chilled and frozen semen.
- Transcervical insemination.
- Breeding soundness evaluation.
- Collection and processing of semen for shipment.
- Semen cryopreservation (freezing).
- Pregnancy diagnosis.